Interactor 1: MED6 (P38782)
Mediator of RNA polymerase II transcription subunit 6 (Mediator complex subunit 6)
Gene: MED6

Interactor 2: MED10 (Q06213)
Mediator of RNA polymerase II transcription subunit 10 (Mediator complex subunit 10) (Negative regulator of URS2 protein 2)
Gene: NUT2

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.71 1.00 0.843

The method score is based on:

Property Details
Experiments 16554755, 16758199, 37968396
Identification Methods affinity chromatography technology, two hybrid, tandem affinity purification
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Med10~Med6
Common GO terms GO:0005634 - nucleus
GO:0016592 - mediator complex
GO:0032968 - positive regulation of transcription elongation by RNA polymerase II
GO:0045944 - positive regulation of transcription by RNA polymerase II
GO:0051123 - RNA polymerase II preinitiation complex assembly
and 2 others

more...

Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 295
Sc

1 157
+ Hs
+ Dm
+ At
+ At

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024