HitPredict

Interactor 1: B3KSH4 (B3KSH4)
Huntingtin interacting protein 2, isoform CRA_a (cDNA FLJ36214 fis, clone THYMU2000672, highly similar to Ubiquitin-conjugating enzyme E2-25 kDa)
Gene: HIP2

Interactor 2: MKRN3 (Q13064)
E3 ubiquitin-protein ligase makorin-3 (EC 2.3.2.27) (RING finger protein 63) (RING-type E3 ubiquitin transferase makorin-3) (Zinc finger protein 127)
Gene: MKRN3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.80	0.528

Property	Details
Experiments	19549727
Identification Methods	two hybrid array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	UQ_con~zf-C3HC4
Common GO terms	-
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 97 Hs			1 507
+	Hs
		957597 UBE2K_HUMAN (1-97): 6.08e-34: 117: 100.00		MKRN3_HUMAN (1-507): 0: 599: 100.00
+	Hs
		982175 UB2D2_HUMAN (1-51): 8.37e-31: 107: 39.22		MKRN3_HUMAN (1-507): 0: 599: 100.00
+	Hs
		957069 UB2D3_HUMAN (1-51): 1.04e-29: 105: 35.29		MKRN3_HUMAN (1-507): 0: 599: 100.00
+	Hs
		1093742 UB2D4_HUMAN (1-51): 1.2e-29: 104: 39.22		MKRN3_HUMAN (1-507): 0: 599: 100.00
+	Hs
		906653 UB2D1_HUMAN (1-51): 2.38e-29: 103: 39.22		MKRN3_HUMAN (1-507): 0: 599: 100.00
+	Hs
		957725 UBE2N_HUMAN (1-51): 3.48e-24: 90.8: 50.98		MKRN3_HUMAN (1-507): 0: 599: 100.00
+	Hs
		909312 UB2E1_HUMAN (1-50): 2.06e-23: 90.1: 38.00		MKRN3_HUMAN (1-507): 0: 599: 100.00
+	Hs
		957229 UB2D3_HUMAN (1-51): 1.04e-29: 105: 35.29		MKRN1_HUMAN (95-507): 0: 539: 53.61
+	Hs
		1459810 UB2D4_HUMAN (1-51): 1.2e-29: 104: 39.22		MKRN1_HUMAN (95-507): 0: 539: 53.61
+	Hs
		906815 UB2D1_HUMAN (1-51): 2.38e-29: 103: 39.22		MKRN1_HUMAN (95-507): 0: 539: 53.61
+	Hs
		957667 UBE2K_HUMAN (1-97): 6.08e-34: 117: 100.00		MKRN2_HUMAN (94-477): 1.96e-161: 465: 34.88
+	Hs
		75534 B3KSH4_HUMAN (1-97): 3.95e-34: 114: 100.00		MKRN2_HUMAN (94-477): 1.96e-161: 465: 34.88
+	Hs
		982317 UB2D2_HUMAN (1-51): 8.37e-31: 107: 39.22		MKRN2_HUMAN (94-477): 1.96e-161: 465: 34.88
+	Hs
		1429258 UB2D4_HUMAN (1-51): 1.2e-29: 104: 39.22		MKRN2_HUMAN (94-477): 1.96e-161: 465: 34.88
+	Hs
		906779 UB2D1_HUMAN (1-51): 2.38e-29: 103: 39.22		MKRN2_HUMAN (94-477): 1.96e-161: 465: 34.88
+	Dm
		683058 UBCD1_DROME (1-51): 3.1e-30: 106: 39.22		Q9VP20_DROME (98-450): 1.43e-123: 368: 36.84