Interactor 1: PSN1 (P97887)
Presenilin-1 (PS-1) (EC 3.4.23.-) (Protein S182) [Cleaved into: Presenilin-1 NTF subunit; Presenilin-1 CTF subunit; Presenilin-1 CTF12 (PS1-CTF12)]
Gene: Psen1

Interactor 2: PEN2 (Q6QI68)
Gamma-secretase subunit PEN-2 (Liver regeneration-related protein LRRGT00140) (Presenilin enhancer protein 2)
Gene: Psenen

Species: Rattus norvegicus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.33 1.00 0.575

The method score is based on:

Property Details
Experiments 27036734
Identification Methods anti bait coimmunoprecipitation
Interaction Type association

The annotation score is based on:

Property Details
Interacting Pfam domains PEN-2~Presenilin
Common GO terms GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0005794 - Golgi apparatus
GO:0005886 - plasma membrane
GO:0006509 - membrane protein ectodomain proteolysis
and 9 others

more...

Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 468
Rn

1 101
+ Mm
+ Hs
+ Hs
+ Mm
+ Dm
+ At
+ At

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024