HitPredict

Interactor 1: TCPB (P39076)
T-complex protein 1 subunit beta (TCP-1-beta) (CCT-beta)
Gene: CCT2

Interactor 2: H3 (P61830)
Histone H3
Gene: HHT1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.50	0.521

Property	Details
Experiments	22199229, 19536198
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 527 Sc			1 136
+	Hs
		934645 TCPB_HUMAN (2-526): 0: 544: 65.59		H31_HUMAN (1-136): 3.24e-62: 188: 88.97
+	Sc
		792395 TCPH_YEAST (3-527): 0: 537: 32.26		H3_YEAST (1-136): 1.51e-56: 174: 100.00
+	Sc
		760792 TCPG_YEAST (2-522): 0: 527: 27.05		H3_YEAST (1-136): 1.51e-56: 174: 100.00
+	Sc
		730800 TCPB_YEAST (1-527): 0: 553: 100.00		CENPA_YEAST (24-134): 7.32e-41: 137: 53.04
+	Ce
		712054 Q9TZS5_CAEEL (2-522): 0: 535: 30.67		HCP3_CAEEL (11-131): 7.82e-44: 146: 46.77
+	Sc
		730835 TCPH_YEAST (3-527): 0: 537: 32.26		CENPA_YEAST (24-134): 7.32e-41: 137: 53.04
+	Sc
		730801 TCPG_YEAST (2-522): 0: 527: 27.05		CENPA_YEAST (24-134): 7.32e-41: 137: 53.04
+	Sc
		772913 TCPE_YEAST (5-515): 1.24e-77: 256: 35.09		H3_YEAST (1-136): 1.51e-56: 174: 100.00
+	Sc
		730821 TCPE_YEAST (5-515): 1.24e-77: 256: 35.09		CENPA_YEAST (24-134): 7.32e-41: 137: 53.04