HitPredict

Interactor 1: CRFR1 (P34998)
Corticotropin-releasing factor receptor 1 (CRF-R-1) (CRF-R1) (CRFR-1) (Corticotropin-releasing hormone receptor 1) (CRH-R-1) (CRH-R1)
Gene: CRHR1

Interactor 2: MAGI3 (Q5TCQ9)
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 (Membrane-associated guanylate kinase inverted 3) (MAGI-3)
Gene: MAGI3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	23576434
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 415 Hs			1 1481
+	Hs
		155244 AGRB1_HUMAN (3-377): 1.04e-78: 266: 19.69		MAGI3_HUMAN (1-1481): 0: 868: 100.00
+	Hs
		762200 CRFR1_HUMAN (1-415): 3.53e-128: 377: 100.00		PTN13_HUMAN (210-1425): 2.09e-58: 225: 13.15
+	Hs
		299743 CRFR1_HUMAN (1-415): 3.53e-128: 377: 100.00		MPDZ_HUMAN (184-1319): 5.09e-49: 194: 12.92
+	Hs
		762203 CRFR1_HUMAN (1-415): 3.53e-128: 377: 100.00		NHRF3_HUMAN (12-530): 3.3e-36: 147: 13.71
+	Hs
		762205 CRFR1_HUMAN (1-415): 3.53e-128: 377: 100.00		MAGI2_HUMAN (698-1369): 2.74e-34: 146: 15.97
+	Hs
		762201 CRFR1_HUMAN (1-415): 3.53e-128: 377: 100.00		DLG1_HUMAN (15-341): 1.35e-24: 114: 9.39
+	Mm
		770722 CRFR1_MOUSE (1-415): 4.37e-129: 379: 97.59		DLG3_MOUSE (13-398): 2.38e-22: 106: 8.63
+	Hs
		762199 CRFR1_HUMAN (1-415): 3.53e-128: 377: 100.00		DLG4_HUMAN (357-687): 3.82e-21: 102: 12.26
+	Hs
		762202 CRFR1_HUMAN (1-415): 3.53e-128: 377: 100.00		SCRIB_HUMAN (16-566): 1.66e-18: 94.5: 16.00
+	Mm
		770723 CRFR1_MOUSE (1-415): 4.37e-129: 379: 97.59		DLG4_MOUSE (800-939): 4.52e-18: 92.5: 21.09
+	Mm
		1223593 AGRL3_MOUSE (1-413): 6.86e-117: 374: 19.18		DLG4_MOUSE (800-939): 4.52e-18: 92.5: 21.09
+	Mm
		1223592 AGRL1_MOUSE (6-413): 4.81e-112: 360: 18.20		DLG4_MOUSE (800-939): 4.52e-18: 92.5: 21.09
+	Hs
		762206 CRFR1_HUMAN (1-415): 3.53e-128: 377: 100.00		MAGI1_HUMAN (974-1378): 5.9e-11: 69.7: 13.64
+	Hs
		338644 AGRL2_HUMAN (1-413): 1.96e-114: 367: 19.63		PARD3_HUMAN (20-270): 4.1e-09: 63.6: 10.63
+	Hs
		155247 AGRB1_HUMAN (3-377): 1.04e-78: 266: 19.69		MAGI2_HUMAN (698-1369): 2.74e-34: 146: 15.97
+	Hs
		155239 AGRB1_HUMAN (3-377): 1.04e-78: 266: 19.69		DLG1_HUMAN (15-341): 1.35e-24: 114: 9.39
+	Hs
		873888 GIPR_HUMAN (17-413): 3.56e-93: 289: 26.49		LNX1_HUMAN (937-1369): 3.15e-15: 83.2: 12.53
+	Hs
		155238 AGRB1_HUMAN (3-377): 1.04e-78: 266: 19.69		DLG4_HUMAN (357-687): 3.82e-21: 102: 12.26
+	Mm
		1190106 AGRB1_MOUSE (3-377): 4.78e-80: 270: 19.95		DLG4_MOUSE (800-939): 4.52e-18: 92.5: 21.09
+	Mm
		1223604 AGRB3_MOUSE (4-392): 1.69e-79: 269: 19.48		DLG4_MOUSE (800-939): 4.52e-18: 92.5: 21.09