HitPredict

Interactor 1: SPT7 (P35177)
SAGA complex subunit SPT7 (Suppressor of Ty protein 7) (Transcriptional activator SPT7)
Gene: SPT7

Interactor 2: GLE2 (P40066)
mRNA export factor GLE2 (Nuclear pore protein GLE2) (Nucleoporin GLE2) (poly(A) RNA export protein RAE1)
Gene: GLE2

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	21734642
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 1332 Sc			1 365
+	Hs
		1007748 KAT2A_HUMAN (429-536): 2.28e-34: 144: 26.85		RAE1L_HUMAN (1-365): 1.71e-93: 285: 40.27
+	Mm
		1298077 KAT2A_MOUSE (429-536): 2.22e-34: 144: 26.85		RAE1L_MOUSE (16-365): 9.24e-92: 281: 40.34
+	Hs
		1450947 BAZ2A_HUMAN (149-547): 1.19e-75: 279: 15.33		NLE1_HUMAN (237-363): 1.78e-25: 108: 12.50
+	Hs
		1387623 BAZ2A_HUMAN (149-547): 1.19e-75: 279: 15.33		SNR40_HUMAN (251-359): 1.01e-20: 93.9: 14.55
+	Hs
		1450946 BAZ2B_HUMAN (134-547): 2.6e-69: 259: 18.75		NLE1_HUMAN (237-363): 1.78e-25: 108: 12.50
+	Sc
		817850 GCN5_YEAST (435-548): 5.78e-20: 96.4: 29.83		GLE2_YEAST (1-365): 2.83e-84: 261: 100.00
+	Hs
		1387622 BAZ2B_HUMAN (134-547): 2.6e-69: 259: 18.75		SNR40_HUMAN (251-359): 1.01e-20: 93.9: 14.55
+	Hs
		224331 PHIP_HUMAN (256-918): 9.46e-74: 273: 11.66		BUB3_HUMAN (7-184): 6.06e-10: 61.7: 14.43
+	Hs
		903453 SMCA4_HUMAN (179-590): 4.82e-63: 239: 10.35		SNR40_HUMAN (251-359): 1.01e-20: 93.9: 14.55
+	Dm
		674032 BRM_DROME (178-648): 1.26e-58: 224: 10.11		EBI_DROME (254-363): 1e-15: 80.4: 13.82
+	Hs
		224370 BRD7_HUMAN (341-931): 9.93e-58: 214: 12.89		BUB3_HUMAN (7-184): 6.06e-10: 61.7: 14.43
+	Hs
		965128 CBP_HUMAN (330-549): 8.67e-40: 164: 18.94		WDR5_HUMAN (2-65): 2.07e-09: 60: 10.61
+	Hs
		965132 KAT2B_HUMAN (429-544): 6.46e-37: 152: 26.72		WDR5_HUMAN (2-65): 2.07e-09: 60: 10.61
+	Hs
		965131 KAT2A_HUMAN (429-536): 2.28e-34: 144: 26.85		WDR5_HUMAN (2-65): 2.07e-09: 60: 10.61
+	Mm
		965405 KAT2A_MOUSE (429-536): 2.22e-34: 144: 26.85		WDR5_MOUSE (2-65): 2.07e-09: 60: 10.61
+	Dm
		1463919 Q9VTZ1_DROME (428-531): 1.54e-25: 116: 32.69		WDS_DROME (2-68): 1.96e-10: 63.5: 10.15
+	Hs
		1245811 ATAD2_HUMAN (429-725): 1.14e-15: 84.9: 22.46		SNR40_HUMAN (251-359): 1.01e-20: 93.9: 14.55
+	Hs
		639703 TAF1_HUMAN (337-877): 1.68e-21: 104: 13.62		WDR5_HUMAN (2-65): 2.07e-09: 60: 10.61