HitPredict

Interactor 1: SSB2 (P40150)
Ribosome-associated molecular chaperone SSB2 (EC 3.6.4.10) (Heat shock protein SSB2) (Hsp70 chaperone Ssb)
Gene: SSB2

Interactor 2: MRN1 (Q08925)
RNA-binding protein MRN1 (Multicopy suppressor of RSC-NHP6 synthetic lethality protein 1) (Post-transcriptional regulator of 69 kDa)
Gene: MRN1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.50	0.60	0.552

Property	Details
Experiments	23332755, 19536198
Identification Methods	biochemical, tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0010494 - cytoplasmic stress granule
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 613 Sc			1 612
+	Sc
		513050 SSB1_YEAST (1-613): 0: 1118: 99.35		MRN1_YEAST (1-612): 8.85e-141: 424: 100.00
+	Sc
		769338 SSB2_YEAST (1-613): 0: 1122: 100.00		NAB6_YEAST (166-376): 1.17e-58: 214: 23.92
+	Sc
		512550 SSB1_YEAST (1-613): 0: 1118: 99.35		NAB6_YEAST (166-376): 1.17e-58: 214: 23.92
+	Sc
		694064 SSB2_YEAST (1-613): 0: 1122: 100.00		PUB1_YEAST (177-504): 2.95e-31: 128: 15.53
+	Sc
		510658 SSB1_YEAST (1-613): 0: 1118: 99.35		PUB1_YEAST (177-504): 2.95e-31: 128: 15.53
+	Sc
		376806 SSB2_YEAST (1-613): 0: 1122: 100.00		PABP_YEAST (504-601): 2.68e-09: 61.8: 15.24
+	Sc
		376601 SSB1_YEAST (1-613): 0: 1118: 99.35		PABP_YEAST (504-601): 2.68e-09: 61.8: 15.24
+	Hs
		504019 HSP7C_HUMAN (5-612): 0: 897: 60.00		PABP4_HUMAN (35-454): 1.58e-80: 268: 13.53
+	Hs
		503332 HSP7C_HUMAN (5-612): 0: 897: 60.00		PABP1_HUMAN (282-612): 4.19e-45: 171: 13.55
+	Sc
		605317 HSP74_YEAST (9-611): 0: 680: 62.15		PUB1_YEAST (177-504): 2.95e-31: 128: 15.53
+	Sc
		449968 HSP73_YEAST (9-611): 0: 677: 60.66		PUB1_YEAST (177-504): 2.95e-31: 128: 15.53