HitPredict

Interactor 1: TBB4A (P04350)
Tubulin beta-4A chain (Tubulin 5 beta) (Tubulin beta-4 chain)
Gene: TUBB4A

Interactor 2: GRAH (P20718)
Granzyme H (EC 3.4.21.-) (CCP-X) (Cathepsin G-like 2) (CTSGL2) (Cytotoxic T-lymphocyte proteinase) (Cytotoxic serine protease C) (CSP-C)
Gene: GZMH

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 444 Hs			1 246
+	Hs
		428722 TBB3_HUMAN (1-444): 0: 714: 91.44		TRY2_HUMAN (1-244): 5.94e-106: 308: 31.87
+	Hs
		428017 TBB5_HUMAN (1-429): 0: 714: 97.44		GRAH_HUMAN (1-246): 4.91e-102: 298: 100.00
+	Hs
		595528 TBB3_HUMAN (1-444): 0: 714: 91.44		GRAH_HUMAN (1-246): 4.91e-102: 298: 100.00
+	Hs
		427973 TBB5_HUMAN (1-429): 0: 714: 97.44		CATG_HUMAN (1-246): 7.55e-101: 295: 57.32
+	Hs
		1037334 TBB3_HUMAN (1-444): 0: 714: 91.44		KLK6_HUMAN (1-244): 1.1e-99: 292: 30.65
+	Hs
		439334 TBB8_HUMAN (1-427): 0: 702: 90.16		CATG_HUMAN (1-246): 7.55e-101: 295: 57.32
+	Hs
		1037427 TBB3_HUMAN (1-444): 0: 714: 91.44		KLK11_HUMAN (15-244): 5.26e-94: 278: 36.40
+	Hs
		381216 TBB4A_HUMAN (1-427): 0: 709: 100.00		PRSS8_HUMAN (13-246): 8.72e-94: 280: 29.80
+	Hs
		428014 TBB5_HUMAN (1-429): 0: 714: 97.44		TRYB2_HUMAN (14-240): 2.8e-91: 271: 29.76
+	Hs
		589992 TBB3_HUMAN (1-444): 0: 714: 91.44		TRYB2_HUMAN (14-240): 2.8e-91: 271: 29.76
+	Hs
		589991 TBB4B_HUMAN (1-427): 0: 713: 98.60		TRYB2_HUMAN (14-240): 2.8e-91: 271: 29.76
+	Hs
		589997 TBB2B_HUMAN (1-430): 0: 712: 96.74		TRYB2_HUMAN (14-240): 2.8e-91: 271: 29.76
+	Hs
		381121 TBB4A_HUMAN (1-427): 0: 709: 100.00		TRYB2_HUMAN (14-240): 2.8e-91: 271: 29.76
+	Hs
		589993 TBB2A_HUMAN (1-430): 0: 709: 96.28		TRYB2_HUMAN (14-240): 2.8e-91: 271: 29.76
+	Hs
		589994 TBB8_HUMAN (1-427): 0: 702: 90.16		TRYB2_HUMAN (14-240): 2.8e-91: 271: 29.76
+	Hs
		420746 TBB8_HUMAN (1-427): 0: 702: 90.16		KLK1_HUMAN (1-245): 4.51e-91: 270: 31.96
+	Hs
		836354 TBB3_HUMAN (1-444): 0: 714: 91.44		GRAK_HUMAN (4-243): 1.9e-45: 154: 37.95
+	Mm
		371765 TBB4B_MOUSE (1-427): 0: 713: 98.60		CFAD_MOUSE (21-240): 6.77e-43: 147: 34.78
+	Hs
		428023 TBB5_HUMAN (1-429): 0: 714: 97.44		PRTN3_HUMAN (20-246): 6.37e-41: 142: 37.45
+	Hs
		381126 TBB4A_HUMAN (1-427): 0: 709: 100.00		PRTN3_HUMAN (20-246): 6.37e-41: 142: 37.45