Interactor 1: MPH1 (P40562)
ATP-dependent DNA helicase MPH1 (EC 3.6.4.12) (FANCM-like protein 1) (Mutator phenotype protein 1)
Gene: MPH1

Interactor 2: MSH6 (Q03834)
DNA mismatch repair protein MSH6 (MutS protein homolog 6) (Postmeiotic segregation protein 3)
Gene: MSH6

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.73 0.60 0.662

The method score is based on:

Property Details
Experiments 11805826, 31351878, 16429126
Identification Methods tandem affinity purification, affinity chromatography technology
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000400 - four-way junction DNA binding
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0016887 - ATP hydrolysis activity
GO:0036297 - interstrand cross-link repair
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 993
Sc

1 1242
+ Sc
+ Sc
+ Ce

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024