HitPredict

Interactor 1: MTR1A (P48039)
Melatonin receptor type 1A (Mel-1A-R) (Mel1a receptor)
Gene: MTNR1A

Interactor 2: GNAI1 (P63096)
Guanine nucleotide-binding protein G(i) subunit alpha-1 (Adenylate cyclase-inhibiting G alpha protein)
Gene: GNAI1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.67 1.00 0.819

The method score is based on:

Property Details
Experiments 26514267, 17215244
Identification Methods pull down, affinity chromatography technology, tandem affinity purification
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains 7tm_1~G-alpha
Common GO terms GO:0005886 - plasma membrane
GO:0007186 - G protein-coupled receptor signaling pathway
GO:0007193 - adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 350
Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024