HitPredict

Interactor 1: B6GUP8 (B6GUP8)
PH domain-containing protein
Gene: uig-1

Interactor 2: CDC42 (Q05062)
Cell division control protein 42 homolog (CDC42Ce)
Gene: cdc-42

Species: Caenorhabditis elegans

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.80	0.579

Property	Details
Experiments	16055082
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Ras~RhoGEF, Ras~SOS1_NGEF_PH
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 958 Ce			1 191
+	Hs
		988587 ARHG2_HUMAN (38-953): 2.38e-109: 363: 12.55		RAC1_HUMAN (1-191): 1.12e-79: 236: 69.11
+	Hs
		988820 PKHG1_HUMAN (208-943): 1.11e-106: 363: 24.37		RAC1_HUMAN (1-191): 1.12e-79: 236: 69.11
+	Hs
		955749 PKHG1_HUMAN (208-943): 1.11e-106: 363: 24.37		CDC42_HUMAN (1-191): 3.92e-77: 230: 86.39
+	Hs
		962349 ARHG2_HUMAN (38-953): 2.38e-109: 363: 12.55		RHOA_HUMAN (5-191): 4.21e-76: 228: 51.87
+	Dm
		74959 B3DN64_DROME (235-796): 1.78e-105: 357: 27.77		RAC1_DROME (1-191): 3.75e-77: 230: 68.75
+	Dm
		828007 Q8MSP7_DROME (235-796): 5.13e-105: 356: 27.77		RAC1_DROME (1-191): 3.75e-77: 230: 68.75
+	Dm
		74960 B3DN64_DROME (235-796): 1.78e-105: 357: 27.77		CDC42_DROME (1-191): 3.61e-76: 228: 88.48
+	Hs
		988545 PREX1_HUMAN (221-868): 1.82e-100: 347: 17.63		RAC1_HUMAN (1-191): 1.12e-79: 236: 69.11
+	Hs
		601497 PKHG1_HUMAN (208-943): 1.11e-106: 363: 24.37		RHOQ_HUMAN (4-191): 1.88e-72: 219: 64.62
+	Dm
		828003 Q7YZA0_DROME (138-576): 1.28e-108: 352: 21.54		RAC1_DROME (1-191): 3.75e-77: 230: 68.75
+	Dm
		1262628 Q7YZA0_DROME (138-576): 1.28e-108: 352: 21.54		Q7JWS8_DROME (2-191): 1.18e-76: 229: 61.26
+	Dm
		874077 Q7YZA0_DROME (138-576): 1.28e-108: 352: 21.54		RAC2_DROME (1-191): 6.88e-76: 227: 67.71
+	Hs
		955401 PREX1_HUMAN (221-868): 1.82e-100: 347: 17.63		CDC42_HUMAN (1-191): 3.92e-77: 230: 86.39
+	Hs
		962299 PREX1_HUMAN (221-868): 1.82e-100: 347: 17.63		RHOA_HUMAN (5-191): 4.21e-76: 228: 51.87
+	Hs
		988472 PREX2_HUMAN (251-868): 6.09e-96: 334: 16.02		RAC1_HUMAN (1-191): 1.12e-79: 236: 69.11
+	Hs
		1015543 PREX2_HUMAN (251-868): 6.09e-96: 334: 16.02		RHOG_HUMAN (1-191): 2.37e-77: 231: 58.12
+	Hs
		955316 PREX2_HUMAN (251-868): 6.09e-96: 334: 16.02		CDC42_HUMAN (1-191): 3.92e-77: 230: 86.39
+	Hs
		962194 PREX2_HUMAN (251-868): 6.09e-96: 334: 16.02		RHOA_HUMAN (5-191): 4.21e-76: 228: 51.87
+	Hs
		955110 TIAM1_HUMAN (21-795): 1.02e-92: 325: 15.59		CDC42_HUMAN (1-191): 3.92e-77: 230: 86.39
+	Hs
		601262 TIAM1_HUMAN (21-795): 1.02e-92: 325: 15.59		RHOQ_HUMAN (4-191): 1.88e-72: 219: 64.62