Interactor 1: RHOA (P61586)
Transforming protein RhoA (EC 3.6.5.2) (Rho cDNA clone 12) (h12)
Gene: RHOA
Interactor 2: ARHG2 (Q92974)
Rho guanine nucleotide exchange factor 2 (Guanine nucleotide exchange factor H1) (GEF-H1) (Microtubule-regulated Rho-GEF) (Proliferating cell nucleolar antigen p40)
Gene: ARHGEF2
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.93 | 1.00 | 0.966 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 9857026, 28514442, 32296183, 33961781, 31871319, 22072711, unassigned1304, 34591642 |
| Identification Methods | enzymatic study, affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation, two hybrid prey pooling approach, two hybrid array, validated two hybrid |
| Interaction Type | direct interaction, physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | PH_16~Ras, Ras~RhoGEF |
| Common GO terms | GO:0000902 - cell morphogenesis GO:0005829 - cytosol GO:0005856 - cytoskeleton GO:0005925 - focal adhesion GO:0031982 - vesicle and 2 others more... |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
