HitPredict

Interactor 1: FGFR2 (P21802)
Fibroblast growth factor receptor 2 (FGFR-2) (EC 2.7.10.1) (K-sam) (KGFR) (Keratinocyte growth factor receptor) (CD antigen CD332)
Gene: FGFR2

Interactor 2: PFKAP (Q01813)
ATP-dependent 6-phosphofructokinase, platelet type (ATP-PFK) (PFK-P) (EC 2.7.1.11) (6-phosphofructokinase type C) (Phosphofructo-1-kinase isozyme C) (PFK-C) (Phosphohexokinase)
Gene: PFKP

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.500

Property	Details
Experiments	35384245
Identification Methods	affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0016020 - membrane
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 821 Hs			1 784
+	Hs
		507955 FGFR1_HUMAN (1-820): 0: 772: 71.17		PFKAP_HUMAN (1-784): 0: 1093: 100.00
+	Hs
		607944 FGFR4_HUMAN (22-810): 0: 684: 55.86		PFKAP_HUMAN (1-784): 0: 1093: 100.00
+	Hs
		966706 NTRK3_HUMAN (166-765): 7.85e-160: 488: 25.31		PFKAP_HUMAN (1-784): 0: 1093: 100.00
+	Hs
		384669 NTRK1_HUMAN (157-765): 4.6e-143: 443: 25.04		PFKAP_HUMAN (1-784): 0: 1093: 100.00
+	Hs
		437718 UFO_HUMAN (5-818): 3.59e-160: 490: 22.49		PFKAM_HUMAN (13-779): 0: 1030: 71.78
+	Hs
		437757 NTRK3_HUMAN (166-765): 7.85e-160: 488: 25.31		PFKAM_HUMAN (13-779): 0: 1030: 71.78
+	Hs
		384121 NTRK1_HUMAN (157-765): 4.6e-143: 443: 25.04		PFKAM_HUMAN (13-779): 0: 1030: 71.78
+	Hs
		437721 FLT3_HUMAN (342-800): 5.44e-85: 293: 36.15		PFKAM_HUMAN (13-779): 0: 1030: 71.78
+	Hs
		729265 VGFR3_HUMAN (42-385): 5.85e-18: 91.4: 17.62		PFKAP_HUMAN (1-784): 0: 1093: 100.00
+	Hs
		966685 TYRO3_HUMAN (167-367): 4.11e-12: 72.1: 22.55		PFKAP_HUMAN (1-784): 0: 1093: 100.00
+	Hs
		572623 VGFR1_HUMAN (5-134): 1.03e-11: 70.9: 16.42		PFKAP_HUMAN (1-784): 0: 1093: 100.00
+	Mm
		519479 PTK7_MOUSE (163-379): 2.55e-18: 92.5: 19.20		PFKAL_MOUSE (19-779): 0: 1023: 69.42
+	Hs
		571668 FGFR3_HUMAN (10-821): 0: 731: 65.69		PFKAL_HUMAN (396-739): 1.72e-65: 234: 27.03
+	Hs
		571677 UFO_HUMAN (5-818): 3.59e-160: 490: 22.49		PFKAL_HUMAN (396-739): 1.72e-65: 234: 27.03
+	Hs
		571707 TIE2_HUMAN (7-763): 1.63e-155: 485: 22.83		PFKAL_HUMAN (396-739): 1.72e-65: 234: 27.03
+	Hs
		384225 NTRK1_HUMAN (157-765): 4.6e-143: 443: 25.04		PFKAL_HUMAN (396-739): 1.72e-65: 234: 27.03
+	Hs
		571682 FLT3_HUMAN (342-800): 5.44e-85: 293: 36.15		PFKAL_HUMAN (396-739): 1.72e-65: 234: 27.03
+	Hs
		571681 VGFR3_HUMAN (42-385): 5.85e-18: 91.4: 17.62		PFKAL_HUMAN (396-739): 1.72e-65: 234: 27.03
+	Hs
		571663 VGFR1_HUMAN (5-134): 1.03e-11: 70.9: 16.42		PFKAL_HUMAN (396-739): 1.72e-65: 234: 27.03