HitPredict

Interactor 1: TCPE (P48643)
T-complex protein 1 subunit epsilon (TCP-1-epsilon) (CCT-epsilon) (Chaperonin containing T-complex polypeptide 1 subunit 5)
Gene: CCT5

Interactor 2: MK06 (Q16659)
Mitogen-activated protein kinase 6 (MAP kinase 6) (MAPK 6) (EC 2.7.11.24) (Extracellular signal-regulated kinase 3) (ERK-3) (MAP kinase isoform p97) (p97-MAPK)
Gene: MAPK6

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	26972000
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 541 Hs			1 721
+	Hs
		826682 TCPG_HUMAN (14-540): 0: 572: 33.15		MK06_HUMAN (1-721): 0: 638: 100.00
+	Hs
		1085489 TCPH_HUMAN (12-539): 0: 570: 29.64		MK06_HUMAN (1-721): 0: 638: 100.00
+	Hs
		573281 TCPA_HUMAN (26-541): 0: 545: 32.08		MK06_HUMAN (1-721): 0: 638: 100.00
+	Hs
		678540 TCPE_HUMAN (1-541): 0: 635: 100.00		MK04_HUMAN (1-575): 2.49e-137: 418: 52.55
+	Hs
		625220 TCPE_HUMAN (1-541): 0: 635: 100.00		CDK2_HUMAN (17-322): 1.11e-133: 398: 31.19
+	Rn
		600455 TCPE_RAT (1-541): 0: 628: 96.49		MK03_RAT (10-362): 7.43e-133: 399: 41.13
+	Hs
		678541 TCPG_HUMAN (14-540): 0: 572: 33.15		MK04_HUMAN (1-575): 2.49e-137: 418: 52.55
+	Hs
		678579 TCPH_HUMAN (12-539): 0: 570: 29.64		MK04_HUMAN (1-575): 2.49e-137: 418: 52.55
+	Rn
		600467 TCPG_RAT (14-540): 0: 575: 32.96		MK03_RAT (10-362): 7.43e-133: 399: 41.13
+	Hs
		625228 TCPG_HUMAN (14-540): 0: 572: 33.15		CDK2_HUMAN (17-322): 1.11e-133: 398: 31.19
+	Sc
		691066 TCPE_YEAST (3-540): 0: 582: 59.89		HOG1_YEAST (3-374): 5.94e-128: 388: 33.78
+	Hs
		625579 TCPH_HUMAN (12-539): 0: 570: 29.64		CDK2_HUMAN (17-322): 1.11e-133: 398: 31.19
+	Hs
		573140 TCPA_HUMAN (26-541): 0: 545: 32.08		MK04_HUMAN (1-575): 2.49e-137: 418: 52.55
+	Rn
		600476 TCPD_RAT (22-534): 0: 546: 38.27		MK03_RAT (10-362): 7.43e-133: 399: 41.13
+	Hs
		573132 TCPA_HUMAN (26-541): 0: 545: 32.08		CDK2_HUMAN (17-322): 1.11e-133: 398: 31.19
+	Rn
		600336 TCPA_RAT (26-541): 0: 540: 32.14		MK03_RAT (10-362): 7.43e-133: 399: 41.13
+	Sc
		691072 TCPH_YEAST (7-540): 0: 542: 30.30		HOG1_YEAST (3-374): 5.94e-128: 388: 33.78
+	Sc
		691051 TCPG_YEAST (12-541): 0: 540: 31.98		HOG1_YEAST (3-374): 5.94e-128: 388: 33.78
+	Sc
		539365 TCPH_YEAST (7-540): 0: 542: 30.30		KSS1_YEAST (14-338): 3.59e-121: 368: 37.76
+	Hs
		625246 TCPD_HUMAN (36-533): 1.62e-107: 333: 39.80		CDK2_HUMAN (17-322): 1.11e-133: 398: 31.19