HitPredict

Interactor 1: CLK3 (P49761)
Dual specificity protein kinase CLK3 (EC 2.7.12.1) (CDC-like kinase 3)
Gene: CLK3

Interactor 2: 1433G (P61981)
14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein gamma, N-terminally processed]
Gene: YWHAG

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.85	0.60	0.714

Property	Details
Experiments	32707033, 33961781, 15324660, 17353931, 28514442
Identification Methods	affinity chromatography technology, pull down, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 638 Hs			1 247
+	Hs
		834015 CLK3_HUMAN (1-638): 0: 542: 100.00		1433E_HUMAN (1-244): 2.02e-141: 398: 63.53
+	Hs
		834024 CLK3_HUMAN (1-638): 0: 542: 100.00		1433F_HUMAN (1-246): 2.5e-135: 382: 86.99
+	Hs
		683207 CLK3_HUMAN (1-638): 0: 542: 100.00		1433B_HUMAN (2-247): 1.91e-109: 317: 75.40
+	Hs
		834018 CLK3_HUMAN (1-638): 0: 542: 100.00		1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59
+	Hs
		646728 CLK3_HUMAN (1-638): 0: 542: 100.00		1433T_HUMAN (2-245): 5.53e-105: 305: 70.33
+	Hs
		683907 CLK3_HUMAN (1-638): 0: 542: 100.00		1433S_HUMAN (2-245): 1.86e-98: 289: 65.16
+	Hs
		625306 CDK2_HUMAN (301-631): 4.28e-138: 406: 24.26		1433E_HUMAN (1-244): 2.02e-141: 398: 63.53
+	Hs
		833704 CLK1_HUMAN (149-625): 1.2e-137: 412: 48.67		1433G_HUMAN (1-247): 3.15e-139: 392: 100.00
+	Hs
		625296 CDK2_HUMAN (301-631): 4.28e-138: 406: 24.26		1433G_HUMAN (1-247): 3.15e-139: 392: 100.00
+	Hs
		833856 CLK2_HUMAN (149-638): 5.31e-135: 406: 58.52		1433G_HUMAN (1-247): 3.15e-139: 392: 100.00
+	Hs
		625383 CDK2_HUMAN (301-631): 4.28e-138: 406: 24.26		1433F_HUMAN (1-246): 2.5e-135: 382: 86.99
+	Hs
		833868 CLK2_HUMAN (149-638): 5.31e-135: 406: 58.52		1433F_HUMAN (1-246): 2.5e-135: 382: 86.99
+	Hs
		904540 DYR1A_HUMAN (181-637): 4.69e-123: 384: 26.20		1433G_HUMAN (1-247): 3.15e-139: 392: 100.00
+	Hs
		683206 CLK2_HUMAN (149-638): 5.31e-135: 406: 58.52		1433B_HUMAN (2-247): 1.91e-109: 317: 75.40
+	Hs
		625334 CDK2_HUMAN (301-631): 4.28e-138: 406: 24.26		1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59
+	Hs
		625130 CDK2_HUMAN (301-631): 4.28e-138: 406: 24.26		1433T_HUMAN (2-245): 5.53e-105: 305: 70.33
+	Hs
		646727 CLK2_HUMAN (149-638): 5.31e-135: 406: 58.52		1433T_HUMAN (2-245): 5.53e-105: 305: 70.33
+	Hs
		683331 DYR1A_HUMAN (181-637): 4.69e-123: 384: 26.20		1433B_HUMAN (2-247): 1.91e-109: 317: 75.40
+	Hs
		646876 DYR1A_HUMAN (181-637): 4.69e-123: 384: 26.20		1433T_HUMAN (2-245): 5.53e-105: 305: 70.33
+	Hs
		684022 DYR1A_HUMAN (181-637): 4.69e-123: 384: 26.20		1433S_HUMAN (2-245): 1.86e-98: 289: 65.16