Interactor 1: IMDH4 (P50094)
Inosine-5'-monophosphate dehydrogenase 4 (IMP dehydrogenase 4) (IMPD 4) (IMPDH 4) (EC 1.1.1.205)
Gene: IMD4

Interactor 2: IMDH3 (P50095)
Inosine-5'-monophosphate dehydrogenase 3 (IMP dehydrogenase 3) (IMPD 3) (IMPDH 3) (EC 1.1.1.205)
Gene: IMD3

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.970

The method score is based on:

Property Details
Experiments 16429126, 16554755, 18467557, 18719252, 37968396, 22615397, 14759368, unassigned1933
Identification Methods affinity chromatography technology, protein complementation assay, two hybrid, dihydrofolate reductase reconstruction, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains CBS~CBS, IMPDH~IMPDH
Common GO terms GO:0000166 - nucleotide binding
GO:0003729 - mRNA binding
GO:0003938 - IMP dehydrogenase activity
GO:0005737 - cytoplasm
GO:0006177 - GMP biosynthetic process
and 2 others

more...

Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 524
Sc

1 523
+ Sc
+ Sc
+ Sc
+ Sc
+ Sp
+ Hs
+ Hs
+ Hs
+ Dm
+ Sc
+ Sc
+ Sc
+ Cj
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024