HitPredict

Interactor 1: CDN2C (P42773)
Cyclin-dependent kinase 4 inhibitor C (Cyclin-dependent kinase 6 inhibitor) (p18-INK4c) (p18-INK6)
Gene: CDKN2C

Interactor 2: ANR44 (Q8N8A2)
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B (PP6-ARS-B) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-B) (Ankyrin repeat domain-containing protein 44)
Gene: ANKRD44

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.80	0.770

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Ank~Ank_2, Ank_2~Ank_2, Ank_2~Ank_3, Ank_2~Ank_4, Ank~Ank_4, Ank_4~Ank_4
Common GO terms	-
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 168 Hs			1 993
+	Mm
		109253 ANK3_MOUSE (77-168): 4.39e-24: 99.6: 42.39		ANK3_MOUSE (1-561): 2.67e-140: 464: 27.45
+	Hs
		1453796 RAI14_HUMAN (1-135): 1.92e-37: 137: 21.32		ANR50_HUMAN (1-397): 2.57e-101: 349: 27.36
+	Hs
		943925 RIPK4_HUMAN (1-99): 1.04e-26: 106: 28.00		ANK3_HUMAN (539-993): 1.53e-104: 362: 25.77
+	Hs
		1091461 Q9H4D1_HUMAN (1-99): 3.65e-26: 105: 27.00		ANK3_HUMAN (539-993): 1.53e-104: 362: 25.77
+	Hs
		1454798 KDIS_HUMAN (2-159): 2.56e-46: 163: 26.42		ANFY1_HUMAN (441-992): 7.8e-61: 228: 17.79
+	Mm
		1036444 ANS1B_MOUSE (59-156): 6.95e-16: 75.9: 37.00		ANK1_MOUSE (630-992): 6.36e-82: 294: 25.70
+	Hs
		920430 DAPK1_HUMAN (42-168): 7.96e-30: 116: 20.93		ANK2_HUMAN (758-992): 1.61e-46: 184: 22.59
+	Hs
		177330 ANR50_HUMAN (51-168): 1.76e-26: 106: 28.81		ANR28_HUMAN (740-993): 5.26e-48: 188: 29.41
+	Hs
		1030698 TANC2_HUMAN (17-164): 5.58e-27: 107: 22.50		ANK2_HUMAN (758-992): 1.61e-46: 184: 22.59
+	Hs
		177209 ANK3_HUMAN (77-168): 2.7e-25: 103: 41.30		ANR28_HUMAN (740-993): 5.26e-48: 188: 29.41
+	Hs
		943916 RIPK4_HUMAN (1-99): 1.04e-26: 106: 28.00		ANK2_HUMAN (758-992): 1.61e-46: 184: 22.59
+	Hs
		1030692 Q9H4D1_HUMAN (1-99): 3.65e-26: 105: 27.00		ANK2_HUMAN (758-992): 1.61e-46: 184: 22.59
+	Hs
		177203 ANK2_HUMAN (77-168): 9.69e-24: 98.4: 40.22		ANR28_HUMAN (740-993): 5.26e-48: 188: 29.41
+	Mm
		109271 ANK3_MOUSE (77-168): 4.39e-24: 99.6: 42.39		ANK2_MOUSE (758-992): 1.6e-46: 184: 22.59
+	Dr
		47843 A0AR23_DANRE (9-137): 7.88e-15: 72.8: 34.62		ANR52_DANRE (731-993): 6.74e-46: 181: 27.27
+	Hs
		177263 ANR52_HUMAN (9-161): 7.81e-09: 55.5: 33.55		ANR28_HUMAN (740-993): 5.26e-48: 188: 29.41
+	Hs
		177291 EHMT2_HUMAN (107-168): 8.69e-09: 55.3: 22.22		ANR28_HUMAN (740-993): 5.26e-48: 188: 29.41
+	Hs
		274188 ANR17_HUMAN (3-166): 8.65e-19: 84.5: 20.10		ANKH1_HUMAN (828-992): 2.7e-34: 145: 24.85