HitPredict

Interactor 1: ZAP70 (P43403)
Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-chain associated protein) (Syk-related tyrosine kinase)
Gene: ZAP70

Interactor 2: TBA1A (Q71U36)
Tubulin alpha-1A chain (EC 3.6.5.-) (Alpha-tubulin 3) (Tubulin B-alpha-1) (Tubulin alpha-3 chain) [Cleaved into: Detyrosinated tubulin alpha-1A chain]
Gene: TUBA1A

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.52	0.60	0.561

Property	Details
Experiments	8530437
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 619 Hs			1 451
+	Hs
		849062 ZAP70_HUMAN (1-619): 0: 641: 100.00		TBA1B_HUMAN (1-440): 0: 712: 99.55
+	Hs
		457292 ZAP70_HUMAN (1-619): 0: 641: 100.00		TBB5_HUMAN (1-439): 0: 696: 40.77
+	Hs
		849194 KSYK_HUMAN (1-600): 0: 559: 52.94		TBA1A_HUMAN (1-451): 0: 710: 100.00
+	Hs
		457293 KSYK_HUMAN (1-600): 0: 559: 52.94		TBB5_HUMAN (1-439): 0: 696: 40.77
+	Hs
		710166 EPHA2_HUMAN (20-614): 2.72e-152: 465: 23.69		TBA1B_HUMAN (1-440): 0: 712: 99.55
+	Hs
		996958 EPHA7_HUMAN (70-606): 5.93e-147: 452: 23.35		TBA4A_HUMAN (1-450): 0: 714: 96.00
+	Hs
		439902 LCK_HUMAN (58-608): 6.16e-159: 467: 26.96		TBB5_HUMAN (1-439): 0: 696: 40.77
+	Hs
		1147355 EPHA7_HUMAN (70-606): 5.93e-147: 452: 23.35		TBA1A_HUMAN (1-451): 0: 710: 100.00
+	Hs
		440022 LCK_HUMAN (58-608): 6.16e-159: 467: 26.96		TBB4B_HUMAN (1-437): 0: 694: 40.50
+	Hs
		710806 EPHB2_HUMAN (70-611): 1.44e-143: 444: 24.29		TBA1B_HUMAN (1-440): 0: 712: 99.55
+	Hs
		457456 EPHA7_HUMAN (70-606): 5.93e-147: 452: 23.35		TBB5_HUMAN (1-439): 0: 696: 40.77
+	Hs
		557213 SRC_HUMAN (103-607): 4.15e-145: 432: 25.49		TBA4A_HUMAN (1-450): 0: 714: 96.00
+	Hs
		557212 SRC_HUMAN (103-607): 4.15e-145: 432: 25.49		TBA1B_HUMAN (1-440): 0: 712: 99.55
+	Hs
		457332 EPHA4_HUMAN (72-616): 1.4e-143: 443: 24.21		TBB5_HUMAN (1-439): 0: 696: 40.77
+	Hs
		931935 EPHB4_HUMAN (70-616): 5.7e-137: 425: 24.51		TBA1B_HUMAN (1-440): 0: 712: 99.55
+	Hs
		932054 EPHA4_HUMAN (72-616): 1.4e-143: 443: 24.21		TBB4B_HUMAN (1-437): 0: 694: 40.50
+	Hs
		463606 LYN_HUMAN (75-608): 2.76e-140: 419: 25.47		TBA1A_HUMAN (1-451): 0: 710: 100.00
+	Hs
		457199 SRC_HUMAN (103-607): 4.15e-145: 432: 25.49		TBB5_HUMAN (1-439): 0: 696: 40.77
+	Hs
		457317 BLK_HUMAN (77-608): 3.89e-144: 429: 26.11		TBB5_HUMAN (1-439): 0: 696: 40.77
+	Hs
		834171 CSK_HUMAN (90-599): 2.36e-136: 407: 27.41		TBA1B_HUMAN (1-440): 0: 712: 99.55