HitPredict

Interactor 1: GATA4 (P43694)
Transcription factor GATA-4 (GATA-binding factor 4)
Gene: GATA4

Interactor 2: EP400 (Q96L91)
E1A-binding protein p400 (EC 3.6.4.-) (CAG repeat protein 32) (Domino homolog) (hDomino) (Trinucleotide repeat-containing gene 12 protein) (p400 kDa SWI2/SNF2-related protein)
Gene: EP400

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35182466
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005654 - nucleoplasm GO:0045893 - positive regulation of DNA-templated transcription
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 442 Hs			1 3159
+	Hs
		703279 GATA4_HUMAN (1-442): 5.23e-80: 256: 100.00		SMCA1_HUMAN (1508-2455): 0: 637: 14.43
+	Hs
		243568 GATA4_HUMAN (1-442): 5.23e-80: 256: 100.00		SMCA5_HUMAN (1508-2466): 0: 634: 14.44
+	Hs
		851559 GATA4_HUMAN (1-442): 5.23e-80: 256: 100.00		CHD4_HUMAN (1499-2520): 2.75e-159: 548: 13.32
+	Mm
		607341 GATA1_MOUSE (52-419): 4.6e-38: 144: 32.88		SMCA5_MOUSE (1508-2466): 0: 635: 14.54
+	Hs
		851673 GATA4_HUMAN (1-442): 5.23e-80: 256: 100.00		CHD8_HUMAN (1505-2480): 7.13e-134: 475: 12.52
+	Hs
		851466 GATA4_HUMAN (1-442): 5.23e-80: 256: 100.00		SMCA2_HUMAN (1506-2307): 1.6e-136: 473: 14.77
+	Hs
		1351293 TRPS1_HUMAN (178-437): 1.44e-43: 165: 24.63		CHD5_HUMAN (1543-2521): 7.27e-162: 557: 13.46
+	Hs
		1133032 TRPS1_HUMAN (178-437): 1.44e-43: 165: 24.63		CHD4_HUMAN (1499-2520): 2.75e-159: 548: 13.32
+	Mm
		607339 GATA1_MOUSE (52-419): 4.6e-38: 144: 32.88		CHD4_MOUSE (1499-2534): 1.83e-158: 546: 13.20
+	Hs
		662389 GATA2_HUMAN (54-403): 4.53e-44: 162: 38.66		SMCA2_HUMAN (1506-2307): 1.6e-136: 473: 14.77
+	Hs
		590395 GATA1_HUMAN (90-422): 4.7e-40: 150: 35.44		SMCA2_HUMAN (1506-2307): 1.6e-136: 473: 14.77
+	Hs
		662545 GATA3_HUMAN (43-387): 3.51e-35: 137: 35.17		SMCA2_HUMAN (1506-2307): 1.6e-136: 473: 14.77
+	Hs
		851687 GATA4_HUMAN (1-442): 5.23e-80: 256: 100.00		CHD7_HUMAN (20-953): 6.2e-16: 87.6: 10.79
+	Hs
		851467 GATA4_HUMAN (1-442): 5.23e-80: 256: 100.00		SMCA4_HUMAN (2530-2882): 2.27e-09: 65.7: 10.62
+	Mm
		1063094 GATA4_MOUSE (1-442): 2.78e-78: 251: 86.43		SMCA4_MOUSE (2793-3115): 8.25e-09: 64.1: 9.54
+	Hs
		662511 GATA2_HUMAN (54-403): 4.53e-44: 162: 38.66		CHD7_HUMAN (20-953): 6.2e-16: 87.6: 10.79
+	Hs
		662390 GATA2_HUMAN (54-403): 4.53e-44: 162: 38.66		SMCA4_HUMAN (2530-2882): 2.27e-09: 65.7: 10.62
+	Hs
		662663 GATA3_HUMAN (43-387): 3.51e-35: 137: 35.17		CHD7_HUMAN (20-953): 6.2e-16: 87.6: 10.79
+	Hs
		590396 GATA1_HUMAN (90-422): 4.7e-40: 150: 35.44		SMCA4_HUMAN (2530-2882): 2.27e-09: 65.7: 10.62
+	Mm
		607334 GATA1_MOUSE (52-419): 4.6e-38: 144: 32.88		SMCA4_MOUSE (2793-3115): 8.25e-09: 64.1: 9.54