Interactor 1: NCBP2 (P52298)
Nuclear cap-binding protein subunit 2 (20 kDa nuclear cap-binding protein) (Cell proliferation-inducing gene 55 protein) (NCBP 20 kDa subunit) (CBP20) (NCBP-interacting protein 1) (NIP1)
Gene: NCBP2

Interactor 2: NCBP1 (Q09161)
Nuclear cap-binding protein subunit 1 (80 kDa nuclear cap-binding protein) (CBP80) (NCBP 80 kDa subunit)
Gene: NCBP1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.989

The method score is based on:

Property Details
Experiments 26496610, 7478990, 29997244, 29395067, 24981860, 22365833, 26264872, 12434151, 11545740, 23665581, 17190602, 19668212, 12374755, unassigned1913, 32814053, 32960270, 26382858
Identification Methods affinity chromatography technology, two hybrid, fluorescent resonance energy transfer, proximity labelling technology, x-ray crystallography, anti tag coimmunoprecipitation, comigration in non denaturing gel electrophoresis, molecular sieving, pull down, anti bait coimmunoprecipitation and 5 others

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Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains MIF4G_like~RRM_1, MIF4G_like_2~RRM_1
Common GO terms GO:0000184 - nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0000339 - RNA cap binding
GO:0000340 - RNA 7-methylguanosine cap binding
GO:0000380 - alternative mRNA splicing, via spliceosome
GO:0000398 - mRNA splicing, via spliceosome
and 22 others

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Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 156
Hs

1 790
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ At
+ Sp
+ Sc

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Last updated: 15 Jul 2024