HitPredict

Interactor 1: ERG25 (P53045)
C-4 methylsterol oxidase ERG25 (EC 1.14.18.-) (Ergosterol biosynthetic protein 25) (Sterol-C4-methyl oxidase ERG25) (SMO)
Gene: ERG25

Interactor 2: ERG25 (P53045)
C-4 methylsterol oxidase ERG25 (EC 1.14.18.-) (Ergosterol biosynthetic protein 25) (Sterol-C4-methyl oxidase ERG25) (SMO)
Gene: ERG25

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.613

The method score is based on:

Property	Details
Experiments	16300994, 16093310
Identification Methods	protein complementation assay, ubiquitin reconstruction
Interaction Type	direct interaction, physical association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000170 - sphingosine hydroxylase activity GO:0000248 - C-5 sterol desaturase activity GO:0000254 - C-4 methylsterol oxidase activity GO:0005506 - iron ion binding GO:0005789 - endoplasmic reticulum membrane and 4 others more... GO:0005886 - plasma membrane GO:0006696 - ergosterol biosynthetic process GO:0030148 - sphingolipid biosynthetic process GO:0042284 - sphingolipid delta-4 desaturase activity
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1	309
Sc

1	309

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024