HitPredict

Interactor 1: PLK1 (P53350)
Serine/threonine-protein kinase PLK1 (EC 2.7.11.21) (Polo-like kinase 1) (PLK-1) (Serine/threonine-protein kinase 13) (STPK13)
Gene: PLK1

Interactor 2: PARD3 (Q8TEW0)
Partitioning defective 3 homolog (PAR-3) (PARD-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2-5) (PAR3-alpha)
Gene: PARD3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 603 Hs			1 1356
+	Ce
		711456 PLK1_CAEEL (22-599): 0: 536: 50.58		PAR3_CAEEL (2-1323): 7.36e-60: 228: 16.08
+	Hs
		1073454 KS6A1_HUMAN (1-362): 5.61e-109: 345: 24.87		PAR3L_HUMAN (1-1354): 5.88e-101: 352: 32.37
+	Hs
		1073495 KS6A1_HUMAN (1-362): 5.61e-109: 345: 24.87		PZRN3_HUMAN (126-1085): 4.45e-67: 249: 13.26
+	Hs
		1073494 KS6A1_HUMAN (1-362): 5.61e-109: 345: 24.87		NEB1_HUMAN (36-1074): 1.37e-60: 229: 11.36
+	Rn
		291511 PLK2_RAT (6-587): 1.9e-166: 492: 35.43		MAGI2_RAT (512-732): 8.91e-11: 68.9: 14.03
+	Hs
		1073444 KS6A1_HUMAN (1-362): 5.61e-109: 345: 24.87		MAGI2_HUMAN (68-1181): 1.8e-38: 159: 13.66
+	Hs
		1073434 KS6A1_HUMAN (1-362): 5.61e-109: 345: 24.87		MAGI3_HUMAN (61-1272): 3.28e-32: 139: 10.65
+	Hs
		1073438 KS6A1_HUMAN (1-362): 5.61e-109: 345: 24.87		PZRN4_HUMAN (450-1168): 4.41e-29: 128: 13.00
+	Mm
		1143553 KS6A2_MOUSE (1-367): 4.69e-110: 348: 23.48		DLG4_MOUSE (540-699): 7.89e-23: 107: 27.98
+	Hs
		942348 KS6A1_HUMAN (1-362): 5.61e-109: 345: 24.87		DLG4_HUMAN (540-699): 1.03e-22: 107: 27.98
+	Hs
		1073470 KS6A1_HUMAN (1-362): 5.61e-109: 345: 24.87		MAGI1_HUMAN (354-780): 1.36e-16: 88.1: 14.16
+	Hs
		1073453 KS6A1_HUMAN (1-362): 5.61e-109: 345: 24.87		LNX1_HUMAN (73-395): 1.66e-13: 77.4: 12.79
+	Hs
		1049960 KS6A1_HUMAN (1-362): 5.61e-109: 345: 24.87		SCRIB_HUMAN (66-355): 5.59e-09: 63.1: 12.75
+	Hs
		1049957 KS6A2_HUMAN (1-367): 4.14e-105: 335: 22.43		SCRIB_HUMAN (66-355): 5.59e-09: 63.1: 12.75
+	Hs
		850651 KS6A3_HUMAN (1-326): 1.91e-103: 331: 25.44		SCRIB_HUMAN (66-355): 5.59e-09: 63.1: 12.75
+	Ce
		86411 AIR2_CAEEL (35-314): 4.72e-41: 152: 32.06		C1P635_CAEEL (117-743): 5.12e-65: 242: 16.95