HitPredict

Interactor 1: YAP1 (P46937)
Transcriptional coactivator YAP1 (Yes-associated protein 1) (Protein yorkie homolog) (Yes-associated protein YAP65 homolog)
Gene: YAP1

Interactor 2: ARRD1 (Q8N5I2)
Arrestin domain-containing protein 1 (Alpha-arrestin 1)
Gene: ARRDC1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.84	0.60	0.712

Property	Details
Experiments	29416926, 26186194, 28514442, 33961781, unassigned3799
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 504 Hs			1 433
+	Hs
		132163 WWP2_HUMAN (12-504): 1.09e-117: 368: 16.54		ARRD1_HUMAN (1-433): 5.41e-131: 386: 100.00
+	Hs
		1327835 NED4L_HUMAN (9-504): 6.84e-112: 355: 19.18		ARRD1_HUMAN (1-433): 5.41e-131: 386: 100.00
+	Hs
		1327833 ITCH_HUMAN (3-504): 6.65e-111: 351: 15.47		ARRD1_HUMAN (1-433): 5.41e-131: 386: 100.00
+	Hs
		1327842 SMUF1_HUMAN (55-504): 1.17e-109: 344: 18.62		ARRD1_HUMAN (1-433): 5.41e-131: 386: 100.00
+	Hs
		132178 WWP2_HUMAN (12-504): 1.09e-117: 368: 16.54		ARRD2_HUMAN (2-371): 6.75e-95: 293: 22.36
+	Hs
		132217 WWP2_HUMAN (12-504): 1.09e-117: 368: 16.54		ARRD3_HUMAN (1-373): 1.85e-94: 292: 20.81
+	Hs
		1348888 NED4L_HUMAN (9-504): 6.84e-112: 355: 19.18		ARRD2_HUMAN (2-371): 6.75e-95: 293: 22.36
+	Hs
		1384109 NED4L_HUMAN (9-504): 6.84e-112: 355: 19.18		ARRD3_HUMAN (1-373): 1.85e-94: 292: 20.81
+	Hs
		1348887 ITCH_HUMAN (3-504): 6.65e-111: 351: 15.47		ARRD2_HUMAN (2-371): 6.75e-95: 293: 22.36
+	Hs
		1384104 ITCH_HUMAN (3-504): 6.65e-111: 351: 15.47		ARRD3_HUMAN (1-373): 1.85e-94: 292: 20.81
+	Hs
		132293 WWP2_HUMAN (12-504): 1.09e-117: 368: 16.54		TXNIP_HUMAN (3-360): 7.96e-86: 269: 21.09
+	Hs
		132169 WWP2_HUMAN (12-504): 1.09e-117: 368: 16.54		ARRD4_HUMAN (2-361): 1.41e-82: 261: 24.07
+	Hs
		1400016 NED4L_HUMAN (9-504): 6.84e-112: 355: 19.18		TXNIP_HUMAN (3-360): 7.96e-86: 269: 21.09
+	Hs
		1394610 ITCH_HUMAN (3-504): 6.65e-111: 351: 15.47		TXNIP_HUMAN (3-360): 7.96e-86: 269: 21.09
+	Hs
		1336059 NED4L_HUMAN (9-504): 6.84e-112: 355: 19.18		ARRD4_HUMAN (2-361): 1.41e-82: 261: 24.07
+	Hs
		1336056 ITCH_HUMAN (3-504): 6.65e-111: 351: 15.47		ARRD4_HUMAN (2-361): 1.41e-82: 261: 24.07
+	Hs
		732677 NED4L_HUMAN (9-504): 6.84e-112: 355: 19.18		ARRB2_HUMAN (22-320): 9.25e-72: 233: 16.62
+	Hs
		732673 ITCH_HUMAN (3-504): 6.65e-111: 351: 15.47		ARRB2_HUMAN (22-320): 9.25e-72: 233: 16.62
+	Hs
		882549 NED4L_HUMAN (9-504): 6.84e-112: 355: 19.18		ARRB1_HUMAN (22-339): 5.1e-70: 229: 15.29
+	Hs
		882546 ITCH_HUMAN (3-504): 6.65e-111: 351: 15.47		ARRB1_HUMAN (22-339): 5.1e-70: 229: 15.29