Protein: ARRD2
Arrestin domain-containing protein 2

Gene: ARRD2, ARRDC2
Organism: Homo sapiens
Interactions: 51
UniProt ID: Q8TBH0

Gene Ontology (top 5):
GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0015031 - protein transport
GO:0031410 - cytoplasmic vesicle

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1348894

WWP1
NEDD4-like E3 ubiquitin-protein ligase WWP1

3

20

Small-scale

0.670

High

329468

EPN2
Epsin-2

2

5

High-throughput

0.606

High

1348899

ZRAN1
Ubiquitin thioesterase ZRANB1

2

5

High-throughput

0.606

High

132178

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

20

High-throughput

0.536

High

175913

SET1A
Histone-lysine N-methyltransferase SETD1A

1

1

High-throughput

0.536

High

208543

PJA2
E3 ubiquitin-protein ligase Praja-2

1

6

High-throughput

0.536

High

231736

PEX1
Peroxisomal ATPase PEX1

1

2

High-throughput

0.536

High

289624

U520
U5 small nuclear ribonucleoprotein 200 kDa helicase

1

7

High-throughput

0.536

High

320575

FARP2
FERM, ARHGEF and pleckstrin domain-containing protein 2

1

7

High-throughput

0.536

High

531111

KAP0
cAMP-dependent protein kinase type I-alpha regulatory subunit

1

1

High-throughput

0.536

High

635350

IMDH1
Inosine-5'-monophosphate dehydrogenase 1

1

2

High-throughput

0.536

High

701195

PSB5
Proteasome subunit beta type-5

1

7

High-throughput

0.536

High

856824

BAG6
Large proline-rich protein BAG6

1

20

High-throughput

0.536

High

861230

MAP1B
Microtubule-associated protein 1B

1

17

High-throughput

0.536

High

1125365

FLNC
Filamin-C

1

8

High-throughput

0.536

High

1137113

SART3
Spliceosome associated factor 3, U4/U6 recycling protein

1

16

High-throughput

0.536

High

1146318

L2GL1
Lethal(2) giant larvae protein homolog 1

1

4

High-throughput

0.536

High

1180236

SMU1
WD40 repeat-containing protein SMU1

1

6

High-throughput

0.536

High

1204772

PP6R3
Serine/threonine-protein phosphatase 6 regulatory subunit 3

1

6

High-throughput

0.536

High

1212808

UBR4
E3 ubiquitin-protein ligase UBR4

1

7

High-throughput

0.536

High

1280352

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

20

High-throughput

0.536

High

1339817

PJA1
E3 ubiquitin-protein ligase Praja-1

1

5

High-throughput

0.536

High

1348885

HDAC2
Histone deacetylase 2

1

5

High-throughput

0.536

High

1348886

USP9X
Ubiquitin carboxyl-terminal hydrolase 9X

1

8

High-throughput

0.536

High

1348887

ITCH
E3 ubiquitin-protein ligase Itchy homolog

1

20

High-throughput

0.536

High

1348888

NED4L
E3 ubiquitin-protein ligase NEDD4-like

1

20

High-throughput

0.536

High

1348889

RANB9
Ran-binding protein 9

1

6

High-throughput

0.536

High

1348891

TBA1C
Tubulin alpha-1C chain

1

13

High-throughput

0.536

High

1348893

ZCHC2
Zinc finger CCHC domain-containing protein 2

1

2

High-throughput

0.536

High

1348895

WDR6
tRNA

1

5

High-throughput

0.536

High

1348896

KCMF1
E3 ubiquitin-protein ligase KCMF1

1

5

High-throughput

0.536

High

1348897

HECW2
E3 ubiquitin-protein ligase HECW2

1

20

High-throughput

0.536

High

1348900

DDX20
Probable ATP-dependent RNA helicase DDX20

1

8

High-throughput

0.536

High

1348902

E41L3
Band 4.1-like protein 3

1

8

High-throughput

0.536

High

890860

TSC2
Tuberin

1

0

High-throughput

0.513

High

905451

HCFC1
Host cell factor 1

1

0

High-throughput

0.513

High

944523

GEMI4
Gem-associated protein 4

1

0

High-throughput

0.513

High

67486

ZSWM8
Zinc finger SWIM domain-containing protein 8

1

1

High-throughput

0.489

High

210999

PSMD3
26S proteasome non-ATPase regulatory subunit 3

1

1

High-throughput

0.489

High

317895

LTN1
E3 ubiquitin-protein ligase listerin

1

1

High-throughput

0.489

High

667378

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

6

High-throughput

0.489

High

874178

PSMD8
26S proteasome non-ATPase regulatory subunit 8

1

1

High-throughput

0.489

High

933694

PSMD4
26S proteasome non-ATPase regulatory subunit 4

1

4

High-throughput

0.489

High

1083406

CPSF1
Cleavage and polyadenylation specificity factor subunit 1

1

2

High-throughput

0.489

High

1147543

UBE3C
Ubiquitin-protein ligase E3C

1

20

High-throughput

0.489

High

1338693

BD1L1
Biorientation of chromosomes in cell division protein 1-like 1

1

9

High-throughput

0.489

High

1348890

PSMD1
26S proteasome non-ATPase regulatory subunit 1

1

5

High-throughput

0.489

High

1348898

ASH2L
Set1/Ash2 histone methyltransferase complex subunit ASH2

1

6

High-throughput

0.489

High

1348901

PSD13
26S proteasome non-ATPase regulatory subunit 13

1

1

High-throughput

0.489

High

58879

PIPSL
Putative PIP5K1A and PSMD4-like protein

1

7

High-throughput

0.445

High

1348892

GCP2
Gamma-tubulin complex component 2

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025