HitPredict

Interactor 1: ARP3 (P47117)
Actin-related protein 3 (Actin-like protein ARP3) (Actin-like protein 3)
Gene: ARP3

Interactor 2: AIM7 (Q12156)
Protein AIM7 (Altered inheritance rate of mitochondria protein 7)
Gene: AIM7

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.70	1.00	0.840

Property	Details
Experiments	23727094, 30042427, 20362448
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	Actin~Cofilin_ADF
Common GO terms	GO:0003779 - actin binding GO:0030479 - actin cortical patch
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 449 Sc			1 149
+	Sp
		151714 ARP3_SCHPO (1-446): 0: 606: 68.01		GMF1_SCHPO (2-146): 2.97e-32: 113: 28.28
+	Hs
		952697 ACTB_HUMAN (1-444): 0: 521: 32.44		DEST_HUMAN (1-146): 3.35e-50: 159: 16.77
+	Hs
		955818 ACTG_HUMAN (3-444): 0: 521: 32.36		DEST_HUMAN (1-146): 3.35e-50: 159: 16.77
+	Hs
		955834 Q1KLZ0_HUMAN (1-444): 0: 521: 32.44		DEST_HUMAN (1-146): 3.35e-50: 159: 16.77
+	Hs
		660017 ACTB_HUMAN (1-444): 0: 521: 32.44		COF1_HUMAN (1-146): 3.07e-46: 149: 18.59
+	Hs
		660028 ACTG_HUMAN (3-444): 0: 521: 32.36		COF1_HUMAN (1-146): 3.07e-46: 149: 18.59
+	Hs
		660081 Q1KLZ0_HUMAN (1-444): 0: 521: 32.44		COF1_HUMAN (1-146): 3.07e-46: 149: 18.59
+	Rn
		852477 ACTB_RAT (1-444): 0: 521: 32.44		COF1_RAT (1-146): 3.62e-46: 149: 18.59
+	Hs
		1168811 Q1KLZ0_HUMAN (1-444): 0: 521: 32.44		Q549N0_HUMAN (1-146): 3.43e-45: 147: 19.87
+	Hs
		952874 ACTB_HUMAN (1-444): 0: 521: 32.44		Q549N0_HUMAN (1-146): 3.43e-45: 147: 19.87
+	Hs
		953195 ACTB_HUMAN (1-444): 0: 521: 32.44		COF2_HUMAN (1-146): 3.43e-45: 147: 19.87
+	Hs
		993207 ACTG_HUMAN (3-444): 0: 521: 32.36		Q549N0_HUMAN (1-146): 3.43e-45: 147: 19.87
+	Hs
		993390 ACTG_HUMAN (3-444): 0: 521: 32.36		COF2_HUMAN (1-146): 3.43e-45: 147: 19.87
+	Hs
		952698 ACTB_HUMAN (1-444): 0: 521: 32.44		GMFB_HUMAN (6-146): 8.89e-39: 129: 24.11
+	Hs
		955875 ACTG_HUMAN (3-444): 0: 521: 32.36		GMFB_HUMAN (6-146): 8.89e-39: 129: 24.11
+	Dm
		534349 ACT5_DROME (1-444): 0: 521: 32.22		CADF_DROME (1-147): 4.36e-22: 87.5: 13.82
+	Hs
		952893 ACTB_HUMAN (1-444): 0: 521: 32.44		TWF2_HUMAN (13-149): 2.66e-11: 61.7: 19.42
+	Hs
		993215 ACTG_HUMAN (3-444): 0: 521: 32.36		TWF2_HUMAN (13-149): 2.66e-11: 61.7: 19.42
+	Hs
		952782 ACTB_HUMAN (1-444): 0: 521: 32.44		TWF1_HUMAN (3-146): 6.64e-10: 57.8: 17.12
+	Hs
		993148 ACTG_HUMAN (3-444): 0: 521: 32.36		TWF1_HUMAN (3-146): 6.64e-10: 57.8: 17.12