HitPredict

Interactor 1: KSYK (P48025)
Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase)
Gene: Syk

Interactor 2: WIPF1 (Q8K1I7)
WAS/WASL-interacting protein family member 1 (Wiskott-Aldrich syndrome protein-interacting protein) (WASP-interacting protein)
Gene: WIPF1

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	14757742
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 629 Mm			1 493
+	Hs
		590259 ZAP70_HUMAN (5-629): 0: 569: 53.04		MUC1_HUMAN (47-489): 1.28e-25: 113: 15.11
+	Hs
		362149 ABL1_HUMAN (161-626): 3.44e-124: 396: 30.64		MUC1_HUMAN (47-489): 1.28e-25: 113: 15.11
+	Hs
		362262 ABL1_HUMAN (161-626): 3.44e-124: 396: 30.64		SOS1_HUMAN (135-462): 8.61e-21: 98.3: 17.51
+	Hs
		541533 FGFR1_HUMAN (115-629): 2.74e-119: 375: 24.23		TGO1_HUMAN (132-389): 4.82e-27: 117: 28.87
+	Hs
		541610 FGFR1_HUMAN (115-629): 2.74e-119: 375: 24.23		WIPF2_HUMAN (14-493): 5.67e-27: 114: 36.18
+	Hs
		299548 EPHA7_HUMAN (67-629): 7.83e-130: 407: 21.69		TRIO_HUMAN (245-438): 1.62e-14: 78.6: 25.91
+	Hs
		323827 FGFR1_HUMAN (115-629): 2.74e-119: 375: 24.23		SC31A_HUMAN (130-422): 2.27e-21: 100: 18.33
+	Hs
		323876 NTRK3_HUMAN (141-628): 3.43e-119: 375: 21.85		SC31A_HUMAN (130-422): 2.27e-21: 100: 18.33
+	Hs
		176239 ABL1_HUMAN (161-626): 3.44e-124: 396: 30.64		SYNJ2_HUMAN (5-406): 4.57e-10: 64.4: 15.64
+	Hs
		299550 NTRK3_HUMAN (141-628): 3.43e-119: 375: 21.85		TRIO_HUMAN (245-438): 1.62e-14: 78.6: 25.91
+	Hs
		215899 FGFR1_HUMAN (115-629): 2.74e-119: 375: 24.23		SYNJ1_HUMAN (252-493): 5.04e-10: 64.5: 20.40
+	Hs
		362705 EGFR_HUMAN (371-613): 2.68e-56: 208: 43.50		MUC1_HUMAN (47-489): 1.28e-25: 113: 15.11
+	Hs
		590283 ERBB4_HUMAN (371-613): 3.08e-56: 208: 43.50		MUC1_HUMAN (47-489): 1.28e-25: 113: 15.11
+	Hs
		1050976 FAK1_HUMAN (338-620): 4.44e-58: 213: 39.65		SOS1_HUMAN (135-462): 8.61e-21: 98.3: 17.51
+	Hs
		410888 ERBB2_HUMAN (371-613): 9.67e-52: 194: 42.28		TGO1_HUMAN (132-389): 4.82e-27: 117: 28.87
+	Hs
		410586 ERBB2_HUMAN (371-613): 9.67e-52: 194: 42.28		MUC1_HUMAN (47-489): 1.28e-25: 113: 15.11
+	Hs
		363175 EGFR_HUMAN (371-613): 2.68e-56: 208: 43.50		SOS1_HUMAN (135-462): 8.61e-21: 98.3: 17.51
+	Hs
		323817 ERBB2_HUMAN (371-613): 9.67e-52: 194: 42.28		SC31A_HUMAN (130-422): 2.27e-21: 100: 18.33
+	Hs
		363641 EGFR_HUMAN (371-613): 2.68e-56: 208: 43.50		TITIN_HUMAN (143-349): 5.31e-09: 61.3: 19.71
+	Hs
		176240 FYN_HUMAN (1-108): 1.54e-44: 168: 26.72		SYNJ2_HUMAN (5-406): 4.57e-10: 64.4: 15.64