HitPredict

Interactor 1: RHO1 (P48148)
Ras-like GTP-binding protein Rho1
Gene: RHO1

Interactor 2: CONU (Q8T0G4)
Rho GTPase-activating protein conundrum
Gene: CONU

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	23468526
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~RhoGAP
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0007165 - signal transduction GO:0045179 - apical cortex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 192 Dm			1 629
+	Hs
		65907 RAC1_HUMAN (1-192): 4.1e-79: 235: 57.73		RHG42_HUMAN (6-604): 9.61e-97: 317: 13.84
+	Hs
		260707 RAC1_HUMAN (1-192): 4.1e-79: 235: 57.73		OPHN1_HUMAN (3-610): 9.99e-89: 294: 11.48
+	Mm
		988897 RAC1_MOUSE (1-192): 4.1e-79: 235: 57.73		RHG32_MOUSE (5-618): 3.38e-81: 282: 11.29
+	Hs
		67650 RAC1_HUMAN (1-192): 4.1e-79: 235: 57.73		RHG32_HUMAN (9-618): 1.74e-78: 274: 12.38
+	Hs
		212765 RAC1_HUMAN (1-192): 4.1e-79: 235: 57.73		SRGP3_HUMAN (18-625): 3.75e-79: 273: 13.40
+	Mm
		988887 RAC1_MOUSE (1-192): 4.1e-79: 235: 57.73		ABR_MOUSE (13-565): 5.42e-80: 272: 14.51
+	Hs
		539995 RAC1_HUMAN (1-192): 4.1e-79: 235: 57.73		BCR_HUMAN (13-547): 3.76e-77: 269: 14.69
+	Hs
		988277 RAC1_HUMAN (1-192): 4.1e-79: 235: 57.73		RHG04_HUMAN (1-605): 1.6e-78: 269: 15.72
+	Hs
		269537 RAC1_HUMAN (1-192): 4.1e-79: 235: 57.73		SRGP2_HUMAN (18-627): 3.11e-77: 268: 14.57
+	Mm
		988892 RAC1_MOUSE (1-192): 4.1e-79: 235: 57.73		BCR_MOUSE (13-547): 1.47e-76: 267: 14.69
+	Hs
		156404 RAC1_HUMAN (1-192): 4.1e-79: 235: 57.73		RHG33_HUMAN (185-623): 3.79e-76: 266: 16.33
+	Hs
		586979 RAC1_HUMAN (1-192): 4.1e-79: 235: 57.73		CHIN_HUMAN (181-565): 2.39e-77: 255: 15.80
+	Sp
		207213 RHO1_SCHPO (2-192): 7.6e-93: 270: 69.00		RGA1_SCHPO (318-573): 2.53e-55: 205: 25.19
+	Sc
		448520 RHO1_YEAST (3-184): 2.84e-91: 267: 72.53		LRG1_YEAST (240-582): 3.74e-56: 207: 22.68
+	Hs
		914009 RAC1_HUMAN (1-192): 4.1e-79: 235: 57.73		CHIO_HUMAN (163-565): 3.72e-71: 239: 16.55
+	Hs
		988417 RAC1_HUMAN (1-192): 4.1e-79: 235: 57.73		RHG15_HUMAN (251-570): 6.27e-71: 239: 18.61
+	Mm
		988900 RAC1_MOUSE (1-192): 4.1e-79: 235: 57.73		RHG22_MOUSE (294-621): 2.62e-68: 237: 21.49
+	Hs
		988402 RAC1_HUMAN (1-192): 4.1e-79: 235: 57.73		RHG44_HUMAN (230-604): 2.15e-66: 234: 18.70
+	Mm
		988896 RAC1_MOUSE (1-192): 4.1e-79: 235: 57.73		CHIO_MOUSE (272-565): 6.65e-69: 229: 16.45
+	Hs
		324254 RAC1_HUMAN (1-192): 4.1e-79: 235: 57.73		FA13A_HUMAN (338-529): 1.02e-09: 63.9: 31.80