Interactor 1: RD23B (P54727)
UV excision repair protein RAD23 homolog B (HR23B) (hHR23B) (XP-C repair-complementing complex 58 kDa protein) (p58)
Gene: RAD23B

Interactor 2: XPC (Q01831)
DNA repair protein complementing XP-C cells (Xeroderma pigmentosum group C-complementing protein) (p125)
Gene: XPC

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.986

The method score is based on:

Property Details
Experiments 28514442, 28473198, 24981860, 33961781, 9372923, 9734359, 21962512, 22431748, 28760956, 11279143, 34591612, 17154534, 9372924, 10873465, 9164480, 24258024, 10488153, 34591642
Identification Methods affinity chromatography technology, biochemical, pull down, two hybrid, anti tag coimmunoprecipitation
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Rad4~XPC-binding
Common GO terms GO:0003684 - damaged DNA binding
GO:0003697 - single-stranded DNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
and 4 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 409
Hs

1 940
+ Hs
+ Mm
+ At
+ Sp
+ Hs
+ Sc
+ Mm
+ Hs
+ Sc
+ Sc
+ Hs
+ Dm
+ Hs
+ Ce
+ Mm

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Last updated: 15 Jul 2024