HitPredict

Interactor 1: SUMO (P55853)
Small ubiquitin-related modifier (SUMO) (Ubiquitin-like protein SMT3)
Gene: smo-1

Interactor 2: UBC9 (Q95017)
SUMO-conjugating enzyme UBC9 (EC 2.3.2.-) (RING-type E3 SUMO transferase UBC9) (SUMO-protein ligase) (Ubiquitin carrier protein 9) (Ubiquitin-conjugating enzyme E2 9) (Ubiquitin-protein ligase 9)
Gene: ubc-9

Species: Caenorhabditis elegans

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.84	1.00	0.918

Property	Details
Experiments	19123269, 31243051, 14704431, 14711411, 11731503
Identification Methods	two hybrid, enzymatic study, two hybrid array, two hybrid pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	Rad60-SLD~UQ_con
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0002119 - nematode larval development GO:0005634 - nucleus GO:0009792 - embryo development ending in birth or egg hatching GO:0016925 - protein sumoylation
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 91 Ce			1 166
+	Hs
		102167 SUMO5_HUMAN (2-90): 1.95e-34: 115: 57.30		Q7KZS0_HUMAN (1-137): 4.21e-81: 239: 78.10
+	Hs
		928121 SUMO1_HUMAN (2-90): 1.03e-34: 115: 58.43		Q7KZS0_HUMAN (1-137): 4.21e-81: 239: 78.10
+	At
		1114967 SUMO2_ARATH (4-90): 1.63e-37: 123: 47.13		SCE1_ARATH (2-157): 1.23e-74: 222: 59.62
+	At
		1114966 SUMO3_ARATH (3-91): 1.99e-35: 118: 35.96		SCE1_ARATH (2-157): 1.23e-74: 222: 59.62
+	Mm
		930505 SUMO3_MOUSE (1-90): 1.3e-39: 128: 44.57		UBC9_MOUSE (1-156): 6.24e-71: 212: 76.92
+	At
		878960 SUMO1_ARATH (3-88): 1.64e-35: 117: 45.35		SCE1_ARATH (2-157): 1.23e-74: 222: 59.62
+	Rn
		930510 SUMO3_RAT (1-90): 2.73e-39: 127: 44.57		UBC9_RAT (1-156): 6.24e-71: 212: 76.92
+	Hs
		902509 SUMO2_HUMAN (1-91): 1.52e-38: 125: 44.68		UBC9_HUMAN (1-156): 6.24e-71: 212: 76.92
+	Hs
		879101 SUMO3_HUMAN (1-91): 4.67e-38: 124: 44.09		UBC9_HUMAN (1-156): 6.24e-71: 212: 76.92
+	Sp
		140897 PMT3_SCHPO (3-90): 1.46e-37: 123: 51.14		UBC9_SCHPO (1-156): 1.44e-68: 206: 60.26
+	Hs
		102156 SUMO5_HUMAN (2-90): 1.95e-34: 115: 57.30		UBC9_HUMAN (1-156): 6.24e-71: 212: 76.92
+	Hs
		928056 SUMO1_HUMAN (2-90): 1.03e-34: 115: 58.43		UBC9_HUMAN (1-156): 6.24e-71: 212: 76.92
+	Mm
		928242 SUMO1_MOUSE (2-90): 1.03e-34: 115: 58.43		UBC9_MOUSE (1-156): 6.24e-71: 212: 76.92
+	Dm
		332535 O97102_DROME (4-90): 7.41e-37: 120: 47.13		Q7KNM2_DROME (1-159): 1.57e-67: 204: 76.73
+	Zm
		74333 B6TQW3_MAIZE (3-88): 7.65e-25: 94.3: 33.72		B4FC97_MAIZE (4-158): 4.01e-75: 222: 32.26
+	At
		1114930 Q8LCF9_ARATH (6-88): 2.4e-24: 92.8: 28.92		SCE1_ARATH (2-157): 1.23e-74: 222: 59.62
+	Mm
		140343 NF2IP_MOUSE (3-83): 8.22e-25: 97.4: 21.95		UBC9_MOUSE (1-156): 6.24e-71: 212: 76.92
+	Sc
		841454 SMT3_YEAST (4-90): 2.2e-30: 105: 40.23		UBC9_YEAST (1-156): 1.16e-59: 184: 53.21