HitPredict

Interactor 1: RIPK4 (P57078)
Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain-containing protein 3) (PKC-delta-interacting protein kinase)
Gene: RIPK4

Interactor 2: FBW1B (Q9UKB1)
F-box/WD repeat-containing protein 11 (F-box and WD repeats protein beta-TrCP2) (F-box/WD repeat-containing protein 1B) (Homologous to Slimb protein) (HOS)
Gene: FBXW11

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.63	0.50	0.565

Property	Details
Experiments	26972000, 32707033, 35914814
Identification Methods	anti tag coimmunoprecipitation, pull down, two hybrid fragment pooling approach
Interaction Type	association, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 832 Hs			1 542
+	Hs
		1330876 Q9H4D1_HUMAN (1-832): 0: 697: 90.75		FBW1B_HUMAN (1-542): 9.69e-174: 503: 100.00
+	Hs
		1302644 Q96T11_HUMAN (1-832): 0: 691: 90.51		FBW1B_HUMAN (1-542): 9.69e-174: 503: 100.00
+	Hs
		883676 RIPK4_HUMAN (1-832): 0: 726: 100.00		FBW1A_HUMAN (26-542): 3.86e-155: 458: 84.59
+	Hs
		72802 RIPK4_HUMAN (1-832): 0: 726: 100.00		B4DH70_HUMAN (40-542): 5.29e-155: 454: 98.41
+	Hs
		1330889 Q9H4D1_HUMAN (1-832): 0: 697: 90.75		FBW1A_HUMAN (26-542): 3.86e-155: 458: 84.59
+	Hs
		1302645 Q96T11_HUMAN (1-832): 0: 691: 90.51		FBW1A_HUMAN (26-542): 3.86e-155: 458: 84.59
+	Hs
		883544 RIPK4_HUMAN (1-832): 0: 726: 100.00		TRAF7_HUMAN (353-522): 1.18e-28: 122: 27.17
+	Hs
		1163035 Q9H4D1_HUMAN (1-832): 0: 697: 90.75		TRAF7_HUMAN (353-522): 1.18e-28: 122: 27.17
+	Hs
		862124 DAPK1_HUMAN (513-831): 7.19e-83: 292: 25.16		FBW1B_HUMAN (1-542): 9.69e-174: 503: 100.00
+	Hs
		1219809 ANKH1_HUMAN (384-541): 3.69e-19: 95.3: 14.47		FBXW7_HUMAN (18-424): 1.12e-72: 246: 20.29
+	Hs
		166894 ANR28_HUMAN (252-539): 5.33e-14: 78.4: 10.62		LIS1_HUMAN (276-542): 4.94e-75: 245: 28.43
+	Hs
		903354 ANKH1_HUMAN (384-541): 3.69e-19: 95.3: 14.47		WDR5_HUMAN (80-265): 5.44e-16: 81.1: 11.92