Interactor 1: SYSC (P49591)
Serine--tRNA ligase, cytoplasmic (EC 6.1.1.11) (Seryl-tRNA synthetase) (SerRS) (Seryl-tRNA(Ser/Sec) synthetase)
Gene: SARS1
Interactor 2: SYSC (P49591)
Serine--tRNA ligase, cytoplasmic (EC 6.1.1.11) (Seryl-tRNA synthetase) (SerRS) (Seryl-tRNA(Ser/Sec) synthetase)
Gene: SARS1
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.41 | 1.00 | 0.647 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 24095058 |
| Identification Methods | x-ray crystallography |
| Interaction Type | direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Seryl_tRNA_N~Seryl_tRNA_N, Seryl_tRNA_N~tRNA-synt_2b, tRNA-synt_2b~tRNA-synt_2b |
| Common GO terms | GO:0000049 - tRNA binding GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0001514 - selenocysteine incorporation GO:0002181 - cytoplasmic translation and 15 others more... |
| Homologous interactions | 14 |
Homologous interactions
Color coding for hit scores 
|
|
|||||||||||||
| + | Dm |   |
|
|||||||||||
| + | Dm | |
|
|||||||||||
| + | Ca | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Ec | |
|
|||||||||||
| + | Mm | |
|
|||||||||||
| + | Mm | |
|
|||||||||||
| + | Cj | |
|
|||||||||||
| + | Sc | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Sc | |
|
|||||||||||
Service provided by Combinatics, Japan
Last updated: 11Aug2025
