Interactor 1: SYSM (Q9JJL8)
Serine--tRNA ligase, mitochondrial (EC 6.1.1.11) (SerRSmt) (Seryl-tRNA synthetase) (SerRS) (Seryl-tRNA(Ser/Sec) synthetase)
Gene: Sars2

Interactor 2: SYSM (Q9JJL8)
Serine--tRNA ligase, mitochondrial (EC 6.1.1.11) (SerRSmt) (Seryl-tRNA synthetase) (SerRS) (Seryl-tRNA(Ser/Sec) synthetase)
Gene: Sars2

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 28130547
Identification Methods cross-linking study
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Seryl_tRNA_N~Seryl_tRNA_N, Seryl_tRNA_N~tRNA-synt_2b, tRNA-synt_2b~tRNA-synt_2b
Common GO terms GO:0004828 - serine-tRNA ligase activity
GO:0005524 - ATP binding
GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix
GO:0006434 - seryl-tRNA aminoacylation
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 518
Mm

1 518
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Sc
+ Ca
+ Hs
+ Ec
+ Cj
+ Dm
+ Mm
+ Sc
+ Hs
+ Ec

Service provided by Combinatics, Japan

Last updated: 11Aug2025