HitPredict

Interactor 1: NU145 (P49687)
Nucleoporin NUP145 (EC 3.4.21.-) (Nuclear pore protein NUP145) [Cleaved into: Nucleoporin NUP145N (N-NUP145); Nucleoporin NUP145C (C-NUP145)]
Gene: NUP145

Interactor 2: MTR10 (Q99189)
mRNA transport regulator MTR10
Gene: MTR10

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	9368759
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0006606 - protein import into nucleus GO:0008139 - nuclear localization sequence binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1317 Sc			1 972
+	Sc
		722084 NU145_YEAST (1-1317): 0: 1092: 100.00		XPO1_YEAST (2-969): 6.87e-139: 445: 13.57
+	Sc
		825190 NU159_YEAST (2-476): 5.67e-17: 89.3: 13.99		MTR10_YEAST (1-972): 0: 633: 100.00
+	Sc
		877996 NUP57_YEAST (73-482): 1.45e-13: 77: 17.65		MTR10_YEAST (1-972): 0: 633: 100.00
+	Hs
		172308 GANP_HUMAN (5-391): 1.16e-17: 91.6: 13.36		XPO1_HUMAN (2-959): 3.02e-161: 503: 12.60
+	Hs
		172603 NUP98_HUMAN (54-517): 2.93e-13: 77: 9.02		XPO1_HUMAN (2-959): 3.02e-161: 503: 12.60
+	Hs
		172585 NU153_HUMAN (2-447): 1.82e-11: 71.2: 10.97		XPO1_HUMAN (2-959): 3.02e-161: 503: 12.60
+	Hs
		172516 NU214_HUMAN (4-435): 7.79e-11: 69.3: 12.18		XPO1_HUMAN (2-959): 3.02e-161: 503: 12.60
+	Sc
		722003 NU159_YEAST (2-476): 5.67e-17: 89.3: 13.99		XPO1_YEAST (2-969): 6.87e-139: 445: 13.57
+	Sc
		722081 NUP57_YEAST (73-482): 1.45e-13: 77: 17.65		XPO1_YEAST (2-969): 6.87e-139: 445: 13.57
+	Sc
		577273 NSP1_YEAST (1-448): 5.02e-13: 75.8: 15.01		XPO1_YEAST (2-969): 6.87e-139: 445: 13.57
+	Hs
		916012 NUP98_HUMAN (54-517): 2.93e-13: 77: 9.02		TNPO1_HUMAN (68-873): 5.07e-133: 424: 12.89
+	Hs
		890382 NU153_HUMAN (2-447): 1.82e-11: 71.2: 10.97		TNPO1_HUMAN (68-873): 5.07e-133: 424: 12.89
+	Hs
		133981 NU153_HUMAN (2-447): 1.82e-11: 71.2: 10.97		IPO5_HUMAN (66-949): 1.36e-124: 407: 13.58
+	Hs
		133960 NU214_HUMAN (4-435): 7.79e-11: 69.3: 12.18		IPO5_HUMAN (66-949): 1.36e-124: 407: 13.58
+	Hs
		164551 NUP98_HUMAN (54-517): 2.93e-13: 77: 9.02		TNPO2_HUMAN (42-865): 1.06e-123: 399: 12.62
+	Hs
		164548 NU153_HUMAN (2-447): 1.82e-11: 71.2: 10.97		TNPO2_HUMAN (42-865): 1.06e-123: 399: 12.62
+	Ce
		264283 Q9U3B9_CAEEL (104-343): 4.74e-18: 92: 21.81		O62332_CAEEL (5-870): 2.45e-106: 353: 11.01
+	Hs
		890401 NU153_HUMAN (2-447): 1.82e-11: 71.2: 10.97		XPO5_HUMAN (1-825): 5.86e-108: 364: 11.76
+	Ce
		264284 Q9XWK3_CAEEL (4-179): 3.68e-12: 72.6: 28.89		O62332_CAEEL (5-870): 2.45e-106: 353: 11.01
+	Sc
		577287 NSP1_YEAST (1-448): 5.02e-13: 75.8: 15.01		XPOT_YEAST (6-770): 4.81e-96: 329: 11.76