HitPredict

Interactor 1: TNPO2 (O14787)
Transportin-2 (Karyopherin beta-2b)
Gene: TNPO2

Interactor 2: NUP98 (P52948)
Nuclear pore complex protein Nup98-Nup96 (EC 3.4.21.-) [Cleaved into: Nuclear pore complex protein Nup98 (98 kDa nucleoporin) (Nucleoporin Nup98) (Nup98); Nuclear pore complex protein Nup96 (96 kDa nucleoporin) (Nucleoporin Nup96) (Nup96)]
Gene: NUP98

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	10875935
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0006606 - protein import into nucleus GO:0008139 - nuclear localization sequence binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 897 Hs			1 1817
+	Hs
		916012 TNPO1_HUMAN (2-897): 0: 629: 84.39		NUP98_HUMAN (1-1817): 0: 1468: 100.00
+	Hs
		915960 IMB1_HUMAN (11-871): 4.15e-93: 315: 17.72		NUP98_HUMAN (1-1817): 0: 1468: 100.00
+	Tt
		107549 G0SGZ5_CHATD (1-897): 4.57e-148: 462: 35.86		NU145_CHATD (3-1716): 0: 596: 19.43
+	Sc
		796100 IMB2_YEAST (2-894): 1.45e-102: 341: 30.25		NU145_YEAST (447-1713): 0: 694: 13.30
+	Hs
		775585 TNPO1_HUMAN (2-897): 0: 629: 84.39		NU214_HUMAN (70-677): 6.48e-19: 96.4: 12.06
+	Ce
		264264 O62332_CAEEL (1-897): 0: 548: 49.72		CO4A1_CAEEL (3-647): 3.07e-43: 176: 10.60
+	Hs
		164548 TNPO2_HUMAN (1-897): 0: 648: 100.00		NU153_HUMAN (90-599): 2.83e-12: 74.4: 15.32
+	Hs
		890382 TNPO1_HUMAN (2-897): 0: 629: 84.39		NU153_HUMAN (90-599): 2.83e-12: 74.4: 15.32
+	Xl
		1216975 Q5U4V0_XENLA (2-897): 0: 618: 83.95		NU153_XENLA (9-548): 2.22e-15: 84.7: 18.09
+	Ce
		264283 O62332_CAEEL (1-897): 0: 548: 49.72		Q9U3B9_CAEEL (217-384): 1.62e-09: 65: 26.11
+	Ce
		264265 O62332_CAEEL (1-897): 0: 548: 49.72		P91457_CAEEL (7-386): 6.9e-09: 63.1: 18.09
+	Xl
		911513 IMB_XENLA (11-871): 3.42e-93: 315: 17.72		Q6DCP4_XENLA (1-610): 3.45e-49: 189: 68.73
+	Sc
		796113 IMB2_YEAST (2-894): 1.45e-102: 341: 30.25		NU100_YEAST (123-761): 6.69e-17: 89.4: 10.75
+	Sc
		796114 IMB2_YEAST (2-894): 1.45e-102: 341: 30.25		NU116_YEAST (182-770): 5.42e-14: 79.8: 10.87
+	At
		1423396 IMB1_ARATH (9-851): 1.32e-103: 343: 15.21		NUP1_ARATH (1-432): 1.17e-12: 75.6: 15.47
+	Sc
		796112 IMB2_YEAST (2-894): 1.45e-102: 341: 30.25		NUP49_YEAST (1-184): 2.3e-13: 76.6: 27.60
+	Hs
		775537 IMB1_HUMAN (11-871): 4.15e-93: 315: 17.72		NU214_HUMAN (70-677): 6.48e-19: 96.4: 12.06
+	Sc
		796098 IMB2_YEAST (2-894): 1.45e-102: 341: 30.25		NUP57_YEAST (1-164): 1.91e-10: 67.7: 27.06
+	Hs
		890320 IMB1_HUMAN (11-871): 4.15e-93: 315: 17.72		NU153_HUMAN (90-599): 2.83e-12: 74.4: 15.32
+	Hs
		1134327 IMB1_HUMAN (11-871): 4.15e-93: 315: 17.72		P121A_HUMAN (95-741): 7.27e-09: 63.2: 9.63