HitPredict

Interactor 1: ACT (P60010)
Actin (EC 3.6.4.-)
Gene: ACT1

Interactor 2: H3 (P61830)
Histone H3
Gene: HHT1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	22977180, 21179020
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006355 - regulation of DNA-templated transcription
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 375 Sc			1 136
+	Hs
		934842 ACTBL_HUMAN (2-375): 0: 687: 83.42		H31_HUMAN (1-136): 3.24e-62: 188: 88.97
+	Hs
		929818 ACTG_HUMAN (1-375): 0: 600: 89.07		H31_HUMAN (1-136): 3.24e-62: 188: 88.97
+	Hs
		929822 ACTG_HUMAN (1-375): 0: 600: 89.07		H33_HUMAN (1-136): 1.25e-61: 187: 90.44
+	Ce
		501470 ACT4_CAEEL (2-375): 0: 598: 89.04		HCP3_CAEEL (11-131): 7.82e-44: 146: 46.77
+	Hs
		828184 ACTB_HUMAN (1-375): 0: 601: 88.80		CENPA_HUMAN (9-133): 2.55e-40: 133: 47.73
+	Sc
		730881 ACT_YEAST (1-375): 0: 594: 100.00		CENPA_YEAST (24-134): 7.32e-41: 137: 53.04