HitPredict

Interactor 1: ACT (P60010)
Actin (EC 3.6.4.-)
Gene: ACT1

Interactor 2: ITT1 (Q04638)
E3 ubiquitin-protein ligase ITT1 (EC 2.3.2.31)
Gene: ITT1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.50	0.457

Property	Details
Experiments	11805837
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 375 Sc			1 464
+	Hs
		1122473 ACTBL_HUMAN (2-375): 0: 687: 83.42		RNF31_HUMAN (95-441): 1.35e-49: 184: 16.95
+	Hs
		227656 ACTBL_HUMAN (2-375): 0: 687: 83.42		PRKN_HUMAN (162-446): 1.01e-43: 161: 16.33
+	Hs
		932245 ACTC_HUMAN (2-375): 0: 591: 87.17		CUL9_HUMAN (95-439): 4.87e-60: 214: 18.34
+	Hs
		891965 ACTB_HUMAN (1-375): 0: 601: 88.80		RNF31_HUMAN (95-441): 1.35e-49: 184: 16.95
+	Hs
		1122451 ACTBL_HUMAN (2-375): 0: 687: 83.42		RN217_HUMAN (180-433): 1.9e-17: 86.9: 22.18
+	Mm
		892218 ACTB_MOUSE (1-375): 0: 601: 88.80		PRKN_MOUSE (162-446): 3.59e-44: 162: 16.33
+	Hs
		227018 ACTB_HUMAN (1-375): 0: 601: 88.80		PRKN_HUMAN (162-446): 1.01e-43: 161: 16.33
+	Hs
		227123 ACTG_HUMAN (1-375): 0: 600: 89.07		PRKN_HUMAN (162-446): 1.01e-43: 161: 16.33
+	Hs
		227128 ACTC_HUMAN (2-375): 0: 591: 87.17		PRKN_HUMAN (162-446): 1.01e-43: 161: 16.33
+	Mm
		933097 ACTS_MOUSE (2-375): 0: 590: 86.90		PRKN_MOUSE (162-446): 3.59e-44: 162: 16.33
+	Hs
		227131 ACTS_HUMAN (2-375): 0: 590: 86.90		PRKN_HUMAN (162-446): 1.01e-43: 161: 16.33
+	Hs
		227086 ACTA_HUMAN (2-375): 0: 589: 86.63		PRKN_HUMAN (162-446): 1.01e-43: 161: 16.33
+	Hs
		915451 ACTA_HUMAN (2-375): 0: 589: 86.63		RN217_HUMAN (180-433): 1.9e-17: 86.9: 22.18