Protein: CTF4
DNA polymerase alpha-binding protein (Chromosome replication protein CHL15) (Chromosome transmission fidelity protein 4) (Protein POB1)

Gene: CTF4
Organism: Saccharomyces cerevisiae S288C
Interactions: 108
UniProt ID: Q01454

Gene Ontology (top 5):
GO:0000228 - nuclear chromosome
GO:0000278 - mitotic cell cycle
GO:0000727 - double-strand break repair via break-induced replication
GO:0003682 - chromatin binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1030397

SLD5
DNA replication complex GINS protein SLD5

20

1

Small-scale

0.990

High

823316

PSF2
DNA replication complex GINS protein PSF2

8

1

Small-scale

0.971

High

1030414

PSF1
DNA replication complex GINS protein PSF1

7

2

Small-scale

0.965

High

1030405

CDC45
Cell division control protein 45

8

1

Small-scale

0.957

High

1030411

PSF3
DNA replication complex GINS protein PSF3

5

0

Small-scale

0.879

High

1030394

CTF4
DNA polymerase alpha-binding protein

3

19

Small-scale

0.871

High

561326

DPOLA
DNA polymerase alpha catalytic subunit A

14

7

Small-scale

0.765

High

721405

MCM4
DNA replication licensing factor MCM4

17

11

Small-scale

0.763

High

664463

MCM3
DNA replication licensing factor MCM3

9

9

Small-scale

0.745

High

713294

MCM5
Minichromosome maintenance protein 5

7

10

Small-scale

0.736

High

1030407

DIA2
Protein DIA2

7

0

Small-scale

0.722

High

1030400

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

4

2

Small-scale

0.698

High

713025

MCM2
DNA replication licensing factor MCM2

4

6

Small-scale

0.676

High

917051

MCM6
DNA replication licensing factor MCM6

4

9

Small-scale

0.676

High

794095

MCM7
DNA replication licensing factor MCM7

3

6

Small-scale

0.646

High

793833

DPOA2
DNA polymerase alpha subunit B

3

0

Small-scale

0.619

High

665197

DPB2
DNA polymerase epsilon subunit B

3

0

Small-scale

0.614

High

524870

HSP71
Heat shock protein SSA1

2

20

High-throughput

0.601

High

806114

DNA2
DNA replication ATP-dependent helicase/nuclease DNA2 [Includes: DNA replication nuclease DNA2

1

8

Small-scale

0.594

High

594518

RPB3
DNA-directed RNA polymerase II subunit RPB3

2

1

High-throughput

0.584

High

647819

RFA1
Replication factor A protein 1

2

7

Small-scale

0.584

High

1025159

SEN1
Helicase SEN1

2

9

Small-scale

0.584

High

393187

HSP82
ATP-dependent molecular chaperone HSP82

2

13

High-throughput

0.571

High

819532

SSB2
Ribosome-associated molecular chaperone SSB2

2

20

High-throughput

0.552

High

677697

MRC1
Mediator of replication checkpoint protein 1

2

0

Small-scale

0.547

High

527448

HSP72
Heat shock protein SSA2

1

20

High-throughput

0.536

High

545931

SSB1
Ribosome-associated molecular chaperone SSB1

1

20

High-throughput

0.536

High

649555

CHL1
ATP-dependent DNA helicase CHL1

1

1

Small-scale

0.536

High

864606

CUL8
Cullin-8

1

20

Small-scale

0.536

High

1030401

MMS1
E3 ubiquitin-protein ligase linker protein MMS1

1

0

Small-scale

0.513

High

821982

PSA6
Proteasome subunit alpha type-6

1

3

High-throughput

0.508

High

602606

PHO85
Cyclin-dependent protein kinase PHO85

1

6

High-throughput

0.501

High

750290

PRP40
Pre-mRNA-processing protein PRP40

1

4

High-throughput

0.501

High

815538

RSP5
E3 ubiquitin-protein ligase RSP5

1

7

High-throughput

0.501

High

1030408

ESA1
Histone acetyltransferase ESA1

1

8

Small-scale

0.501

High

703895

RAD14
DNA repair protein RAD14

1

0

High-throughput

0.493

High

488989

SWI6
Regulatory protein SWI6

1

9

High-throughput

0.479

High

555271

RAD50
DNA repair protein RAD50

1

8

High-throughput

0.479

High

632852

PRI2
DNA primase large subunit

1

1

Small-scale

0.479

High

642070

DPOE
DNA polymerase epsilon catalytic subunit A

1

7

Small-scale

0.479

High

646504

RAD53
Serine/threonine-protein kinase RAD53

1

2

High-throughput

0.479

High

688762

RFA2
Replication factor A protein 2

1

8

Small-scale

0.479

High

707926

TF2B
Transcription initiation factor IIB

1

4

High-throughput

0.479

High

735115

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

3

High-throughput

0.479

High

739726

SPT16
FACT complex subunit SPT16

1

5

High-throughput

0.479

High

748000

SMY2
Protein SMY2

1

2

High-throughput

0.479

High

779316

CENPA
Histone H3-like centromeric protein CSE4

1

15

High-throughput

0.479

High

800967

RFC3
Replication factor C subunit 3

1

6

Small-scale

0.479

High

822967

RFC4
Replication factor C subunit 4

1

5

Small-scale

0.479

High

823139

RFC2
Replication factor C subunit 2

1

5

Small-scale

0.479

High

850555

RSC8
Chromatin structure-remodeling complex protein RSC8

1

8

High-throughput

0.479

High

863400

RSF2
Respiration factor 2

1

2

High-throughput

0.479

High

924174

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

1

17

Small-scale

0.479

High

1030399

POB3
FACT complex subunit POB3

1

8

High-throughput

0.479

High

521127

PRI1
DNA primase small subunit

1

0

Small-scale

0.458

High

586481

PCNA
Proliferating cell nuclear antigen

1

0

Small-scale

0.458

High

668288

UBP1
Ubiquitin carboxyl-terminal hydrolase 1

1

0

High-throughput

0.458

High

674426

RPC4
DNA-directed RNA polymerase III subunit RPC4

1

0

High-throughput

0.458

High

735402

MCM10
Minichromosome maintenance protein 10

1

0

Small-scale

0.458

High

744538

DRI1
Putative RNA-binding protein involved in heterochromatin assembly

1

0

High-throughput

0.458

High

793579

TBS1
Uncharacterized transcriptional regulatory protein TBS1

1

0

High-throughput

0.458

High

1030396

DIG2
Down-regulator of invasive growth 2

1

0

High-throughput

0.458

High

1030409

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

0

High-throughput

0.458

High

1030410

TSR3
18S rRNA aminocarboxypropyltransferase

1

0

High-throughput

0.458

High

646153

NPR1
Nitrogen permease reactivator protein

1

7

High-throughput

0.457

High

822274

DOA10
ERAD-associated E3 ubiquitin-protein ligase DOA10

1

1

High-throughput

0.457

High

850961

TOS3
Serine/threonine-protein kinase TOS3

1

3

High-throughput

0.457

High

676269

MAS5
Mitochondrial protein import protein MAS5

1

13

High-throughput

0.445

High

742194

HSP7F
Heat shock protein homolog SSE1

1

20

High-throughput

0.445

High

742925

HSP79
Heat shock protein homolog SSE2

1

20

High-throughput

0.445

High

804382

SSZ1
Ribosome-associated complex subunit SSZ1

1

13

High-throughput

0.445

High

579908

HSC82
ATP-dependent molecular chaperone HSC82

1

13

High-throughput

0.437

High

597618

CDC23
Anaphase-promoting complex subunit CDC23

1

8

High-throughput

0.437

High

646684

VPS15
Serine/threonine-protein kinase VPS15

1

2

High-throughput

0.437

High

713511

TRXB1
Thioredoxin reductase 1

1

3

High-throughput

0.437

High

734342

DGR2
2-deoxy-glucose resistant protein 2

1

17

High-throughput

0.437

High

746750

KPR1
Ribose-phosphate pyrophosphokinase 1

1

4

High-throughput

0.437

High

758191

ZRT3
Zinc-regulated transporter 3

1

1

High-throughput

0.437

High

792744

ETR1
Enoyl-[acyl-carrier-protein] reductase, mitochondrial

1

3

High-throughput

0.437

High

798427

RGD1
RHO GTPase-activating protein RGD1

1

3

High-throughput

0.437

High

800673

KPR2
Ribose-phosphate pyrophosphokinase 2

1

4

High-throughput

0.437

High

873830

BUL1
Ubiquitin ligase-binding protein BUL1

1

2

High-throughput

0.437

High

916401

PAN2
PAN2-PAN3 deadenylation complex catalytic subunit PAN2

1

10

High-throughput

0.437

High

577196

SEC63
Protein translocation protein SEC63

1

10

High-throughput

0.407

High

592442

VATB
V-type proton ATPase subunit B

1

7

High-throughput

0.407

High

811016

TCPD
T-complex protein 1 subunit delta

1

20

High-throughput

0.407

High

816356

HSP7E
Heat shock protein SSC3, mitochondrial

1

16

High-throughput

0.407

High

816735

PFD2
Prefoldin subunit 2

1

3

High-throughput

0.407

High

836848

MPG1
Mannose-1-phosphate guanyltransferase

1

2

High-throughput

0.407

High

924479

PFD4
Prefoldin subunit 4

1

4

High-throughput

0.407

High

1030398

PFD5
Prefoldin subunit 5

1

5

High-throughput

0.407

High

1030403

SWA2
Auxilin-like clathrin uncoating factor SWA2

1

9

High-throughput

0.407

High

1030412

HSP42
Heat shock protein 42

1

4

High-throughput

0.407

High

1030395

TOF2
Topoisomerase 1-associated factor 2

1

0

Small-scale

0.309

High

704696

PRR1
Serine/threonine-protein kinase PRR1

1

0

High-throughput

0.261

Low

1030413

GDIR
Rho GDP-dissociation inhibitor

1

0

High-throughput

0.251

Low

654799

URE2
Transcriptional regulator URE2

1

0

High-throughput

0.249

Low

758486

SEG2
Eisosome protein SEG2

1

0

High-throughput

0.249

Low

763769

THI80
Thiamine pyrophosphokinase

1

0

High-throughput

0.249

Low

782607

OMA1
Mitochondrial metalloendopeptidase OMA1

1

0

High-throughput

0.249

Low

803055

MUP3
Low-affinity methionine permease

1

0

High-throughput

0.249

Low

817218

FIR1
Factor interacting with REF2

1

0

High-throughput

0.249

Low

917236

YIP5
Protein YIP5

1

0

High-throughput

0.249

Low

1030402

YPQ2
Vacuolar arginine/histidine antiporter YPQ2

1

0

High-throughput

0.249

Low

1030404

YD073
UPF0592 protein YDL073W

1

0

High-throughput

0.249

Low

1030406

YO036
Uncharacterized protein YOL036W

1

0

High-throughput

0.249

Low

863696

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025