HitPredict

Interactor 1: ACTB (P60709)
Actin, cytoplasmic 1 (EC 3.6.4.-) (Beta-actin) [Cleaved into: Actin, cytoplasmic 1, N-terminally processed]
Gene: ACTB

Interactor 2: MTSS2 (Q765P7)
Protein MTSS 2 (Actin-bundling with BAIAP2 homology protein 1) (ABBA-1) (MTSS1-like protein)
Gene: MTSS2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	33961781, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0015629 - actin cytoskeleton GO:0030027 - lamellipodium
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 375 Hs			1 747
+	Hs
		474824 POTEI_HUMAN (1-375): 0: 731: 91.20		MTSS2_HUMAN (1-747): 7.6e-84: 283: 100.00
+	Hs
		200936 ACTBL_HUMAN (2-375): 0: 735: 91.71		MTSS1_HUMAN (5-745): 3.16e-61: 221: 54.42
+	Hs
		554315 ACTBL_HUMAN (2-375): 0: 735: 91.71		MUC1_HUMAN (303-746): 7.84e-24: 109: 11.44
+	Hs
		892117 ACTB_HUMAN (1-375): 0: 603: 100.00		BAIP2_HUMAN (1-565): 2.55e-62: 220: 18.64
+	Hs
		930056 ACTG_HUMAN (1-375): 0: 601: 98.93		BAIP2_HUMAN (1-565): 2.55e-62: 220: 18.64
+	Hs
		932460 ACTC_HUMAN (2-375): 0: 592: 94.12		BAIP2_HUMAN (1-565): 2.55e-62: 220: 18.64
+	Hs
		892093 ACTB_HUMAN (1-375): 0: 603: 100.00		BI2L1_HUMAN (5-534): 6.86e-52: 190: 14.71
+	Hs
		930042 ACTG_HUMAN (1-375): 0: 601: 98.93		BI2L1_HUMAN (5-534): 6.86e-52: 190: 14.71
+	Hs
		932435 ACTC_HUMAN (2-375): 0: 592: 94.12		BI2L1_HUMAN (5-534): 6.86e-52: 190: 14.71
+	Hs
		891932 ACTB_HUMAN (1-375): 0: 603: 100.00		CTTB2_HUMAN (13-604): 2.81e-42: 168: 14.06
+	Hs
		554290 ACTA_HUMAN (2-375): 0: 591: 94.12		MUC1_HUMAN (303-746): 7.84e-24: 109: 11.44
+	Hs
		203220 ACTC_HUMAN (2-375): 0: 592: 94.12		SYNJ1_HUMAN (173-557): 2.93e-11: 69.6: 10.40