HitPredict

Interactor 1: UBE2N (P61088)
Ubiquitin-conjugating enzyme E2 N (EC 2.3.2.23) (Bendless-like ubiquitin-conjugating enzyme) (E2 ubiquitin-conjugating enzyme N) (Ubc13) (UbcH13) (Ubiquitin carrier protein N) (Ubiquitin-protein ligase N)
Gene: UBE2N

Interactor 2: LRRK2 (Q5S007)
Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (EC 3.6.5.-) (Dardarin)
Gene: LRRK2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31046837
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 152 Hs			1 2527
+	Hs
		895805 UB2D3_HUMAN (4-149): 1.46e-78: 230: 45.89		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		851818 UB2E1_HUMAN (1-149): 1.93e-73: 219: 45.64		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		1130805 V9HW41_HUMAN (1-152): 1.51e-73: 218: 100.00		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		1130622 UBE2T_HUMAN (7-148): 1.12e-38: 131: 45.89		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Xl
		919928 UB2D2_XENLA (4-149): 9.96e-80: 233: 46.58		M3K10_XENLA (1865-2136): 9.87e-23: 108: 30.24
+	Mm
		896583 UBE2N_MOUSE (1-152): 1.51e-73: 218: 100.00		M3K7_MOUSE (1869-2132): 1.06e-22: 107: 28.83