Protein: HOME2
Homer protein homolog 2 (Homer-2) (Cupidin)

Gene: HOME2, HOMER2
Organism: Homo sapiens
Interactions: 30
UniProt ID: Q9NSB8

Gene Ontology (top 5):
GO:0003779 - actin binding
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0007216 - G protein-coupled glutamate receptor signaling pathway

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1295217

HOME1
Homer protein homolog 1

5

16

High-throughput

0.927

High

1449299

HOME3
Homer protein homolog 3

2

16

High-throughput

0.811

High

1434411

RNF41
E3 ubiquitin-protein ligase NRDP1

4

10

Small-scale

0.696

High

1360092

PALLD
Palladin

3

11

High-throughput

0.665

High

1160771

DREB
Drebrin

3

8

High-throughput

0.662

High

1449301

ABI3
ABI gene family member 3

3

20

High-throughput

0.647

High

1449300

IFT57
Intraflagellar transport protein 57 homolog

3

2

High-throughput

0.609

High

423278

A4
Amyloid-beta precursor protein

2

2

Small-scale

0.595

High

1411330

LZTS2
Leucine zipper putative tumor suppressor 2

1

20

High-throughput

0.573

High

641345

RYR1
Ryanodine receptor 1

1

8

Small-scale

0.561

High

900188

FXR1
RNA-binding protein FXR1

1

14

High-throughput

0.541

High

447870

TPM3
Tropomyosin alpha-3 chain

1

5

High-throughput

0.536

High

718473

CD6
T-cell differentiation antigen CD6

1

3

High-throughput

0.536

High

1179867

INSY1
Inhibitory synaptic factor 1

1

3

High-throughput

0.536

High

1234759

SPOPL
Speckle-type POZ protein-like

1

4

High-throughput

0.536

High

1287170

MYPN
Myopalladin

1

9

High-throughput

0.536

High

1417966

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

1

20

High-throughput

0.536

High

1046425

UBXN1
UBX domain-containing protein 1

1

0

Small-scale

0.529

High

1339856

PJA1
E3 ubiquitin-protein ligase Praja-1

1

3

Small-scale

0.501

High

1438983

SMUF1
E3 ubiquitin-protein ligase SMURF1

1

9

Small-scale

0.501

High

574037

HXB2
Homeobox protein Hox-B2

1

5

High-throughput

0.489

High

1322148

SYCE1
Synaptonemal complex central element protein 1

1

3

High-throughput

0.489

High

971151

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

12

High-throughput

0.479

High

1169040

CSPP1
Centrosome and spindle pole-associated protein 1

1

1

High-throughput

0.479

High

911125

IMA1
Importin subunit alpha-1

1

0

High-throughput

0.460

High

391485

FRIL
Ferritin light chain

1

2

High-throughput

0.445

High

1325319

PALS1
Protein PALS1

1

6

High-throughput

0.445

High

1341104

INADL
InaD-like protein

1

13

High-throughput

0.445

High

1449302

PNMA2
Paraneoplastic antigen Ma2

1

4

High-throughput

0.407

High

1410464

VKOR1
Vitamin K epoxide reductase complex subunit 1

1

0

Small-scale

0.251

Low


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Last updated: 11Aug2025