HitPredict

Interactor 1: TAB2 (Q9NYJ8)
TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 (Mitogen-activated protein kinase kinase kinase 7-interacting protein 2) (TAK1-binding protein 2) (TAB-2) (TGF-beta-activated kinase 1-binding protein 2)
Gene: TAB2

Interactor 2: RUVB2 (Q9Y230)
RuvB-like 2 (EC 3.6.4.12) (48 kDa TATA box-binding protein-interacting protein) (48 kDa TBP-interacting protein) (51 kDa erythrocyte cytosolic protein) (ECP-51) (INO80 complex subunit J) (Repressing pontin 52) (Reptin 52) (TIP49b) (TIP60-associated protein 54-beta) (TAP54-beta)
Gene: RUVBL2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	14743216
Identification Methods	tandem affinity purification
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 693 Hs			1 463
+	Hs
		1348531 TAB2_HUMAN (1-693): 1.25e-111: 354: 100.00		RUVB1_HUMAN (8-451): 0: 655: 42.67
+	Dm
		631322 BRM_DROME (165-665): 1e-43: 172: 12.74		RUVB1_DROME (8-452): 0: 619: 44.32
+	Hs
		1170098 SRCAP_HUMAN (28-590): 2.21e-09: 63.2: 8.69		RUVB2_HUMAN (1-463): 0: 718: 100.00
+	Mm
		888094 EP400_MOUSE (136-450): 6.08e-14: 78.2: 16.15		RUVB1_MOUSE (8-451): 0: 656: 42.67
+	Hs
		1170099 SRCAP_HUMAN (28-590): 2.21e-09: 63.2: 8.69		RUVB1_HUMAN (8-451): 0: 655: 42.67