HitPredict

Interactor 1: RHOA (P61586)
Transforming protein RhoA (EC 3.6.5.2) (Rho cDNA clone 12) (h12)
Gene: RHOA

Interactor 2: SRGP1 (Q7Z6B7)
SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) (Rho GTPase-activating protein 13)
Gene: SRGAP1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	20856855
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~RhoGAP
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 193 Hs			1 1085
+	Mm
		1265268 RHOA_MOUSE (1-193): 4.1e-81: 240: 99.48		SRGP1_MOUSE (1-1085): 0: 775: 94.84
+	Hs
		900540 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		RHG29_HUMAN (47-1037): 5.51e-108: 367: 14.90
+	Hs
		245183 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		OPHN1_HUMAN (110-919): 1.95e-101: 340: 15.33
+	Hs
		49631 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		RHG10_HUMAN (110-914): 3.41e-101: 339: 14.39
+	Ce
		88245 RAC1_CAEEL (1-193): 2.07e-80: 238: 55.44		D3YT54_CAEEL (459-1008): 1.51e-100: 331: 28.24
+	Hs
		901048 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		RHG26_HUMAN (115-783): 1.93e-95: 324: 13.70
+	Hs
		70663 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		MYO9A_HUMAN (75-970): 5.98e-86: 308: 11.93
+	Hs
		901000 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		RHG23_HUMAN (377-1036): 1.33e-84: 303: 17.34
+	Hs
		64681 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		RHG32_HUMAN (456-1077): 4.76e-84: 302: 17.03
+	Mm
		925803 RAC1_MOUSE (1-193): 8.86e-80: 237: 57.22		RHG32_MOUSE (456-1065): 3.59e-84: 302: 17.19
+	Hs
		900997 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		GMIP_HUMAN (31-899): 6.91e-84: 295: 15.08
+	Hs
		900634 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		RHG22_HUMAN (471-1049): 2.07e-83: 287: 18.32
+	Hs
		900564 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		RHG21_HUMAN (251-1044): 1.44e-78: 285: 16.73
+	Mm
		925802 RAC1_MOUSE (1-193): 8.86e-80: 237: 57.22		CHIO_MOUSE (482-694): 1.27e-80: 268: 32.11
+	Hs
		900954 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		RHG35_HUMAN (496-664): 5.22e-18: 92: 31.36
+	Hs
		506561 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		BCR_HUMAN (494-673): 1.21e-17: 90.9: 30.56
+	Mm
		925798 RAC1_MOUSE (1-193): 8.86e-80: 237: 57.22		BCR_MOUSE (494-673): 9.8e-18: 91.3: 30.56
+	Hs
		900429 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		RHG05_HUMAN (496-693): 2.29e-16: 87: 30.30
+	Hs
		900426 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		ABR_HUMAN (494-672): 4.41e-16: 85.5: 29.05
+	Mm
		925793 RAC1_MOUSE (1-193): 8.86e-80: 237: 57.22		ABR_MOUSE (494-672): 3.68e-16: 85.9: 29.61