HitPredict

Interactor 1: DSH (P51140)
Segment polarity protein dishevelled
Gene: DSH

Interactor 2: Q95TT5 (Q95TT5)
LD24616p
Gene: cno

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.808

Property	Details
Experiments	17183697, 38944040
Identification Methods	anti tag coimmunoprecipitation, two hybrid, anti bait coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	PDZ~PDZ
Common GO terms	GO:0000132 - establishment of mitotic spindle orientation GO:0007391 - dorsal closure GO:0019904 - protein domain specific binding GO:0048730 - epidermis morphogenesis
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 623 Dm			1 2051
+	Dm
		900637 DSH_DROME (1-623): 5.09e-151: 451: 100.00		Q8IPP3_DROME (1-1748): 0: 1082: 66.67
+	Hs
		936314 DLG1_HUMAN (30-615): 2.06e-66: 235: 14.43		AFAD_HUMAN (1-1803): 0: 924: 32.83
+	Dm
		118813 DSH_DROME (1-623): 5.09e-151: 451: 100.00		M9NFI9_DROME (995-1190): 1.57e-30: 134: 22.61
+	Hs
		246079 DVL3_HUMAN (10-615): 1.41e-109: 347: 41.81		KIF1B_HUMAN (312-652): 5.75e-59: 228: 11.91
+	Hs
		159379 DVL1_HUMAN (10-609): 4.14e-116: 363: 41.86		PARD3_HUMAN (910-1726): 2.23e-53: 209: 11.95
+	Hs
		159765 DVL2_HUMAN (10-613): 4.74e-109: 346: 42.23		PARD3_HUMAN (910-1726): 2.23e-53: 209: 11.95
+	Hs
		1091496 DLG1_HUMAN (30-615): 2.06e-66: 235: 14.43		KIF14_HUMAN (189-625): 7.32e-67: 253: 17.52
+	Hs
		1091503 DLG2_HUMAN (43-615): 1.16e-76: 263: 13.74		DLG1_HUMAN (836-1674): 1.82e-55: 212: 8.78
+	Hs
		245927 DLG1_HUMAN (30-615): 2.06e-66: 235: 14.43		KIF1B_HUMAN (312-652): 5.75e-59: 228: 11.91
+	Hs
		1091484 DLG1_HUMAN (30-615): 2.06e-66: 235: 14.43		DLG1_HUMAN (836-1674): 1.82e-55: 212: 8.78
+	Hs
		159776 DVL2_HUMAN (10-613): 4.74e-109: 346: 42.23		DLG3_HUMAN (1011-1289): 9.86e-17: 88.7: 20.35
+	Mm
		1247159 DLG2_MOUSE (43-615): 2.22e-78: 267: 13.41		NEB2_MOUSE (995-1167): 5.92e-38: 156: 28.18
+	Mm
		1247106 DLG1_MOUSE (30-615): 1.69e-69: 244: 13.93		NEB2_MOUSE (995-1167): 5.92e-38: 156: 28.18
+	Mm
		999796 DLG2_MOUSE (43-615): 2.22e-78: 267: 13.41		DLG3_MOUSE (1011-1289): 6.27e-17: 89.5: 20.70
+	Mm
		1223689 DLG2_MOUSE (43-615): 2.22e-78: 267: 13.41		DLG4_MOUSE (1002-1108): 8.45e-17: 88.7: 29.91
+	Hs
		1006071 DLG2_HUMAN (43-615): 1.16e-76: 263: 13.74		DLG4_HUMAN (1002-1108): 8.82e-17: 88.7: 29.91
+	Hs
		1152416 DLG2_HUMAN (43-615): 1.16e-76: 263: 13.74		DLG3_HUMAN (1011-1289): 9.86e-17: 88.7: 20.35
+	Ce
		111231 Q18239_CAEEL (10-496): 1.12e-76: 261: 30.62		DLG1_CAEEL (979-1096): 4.49e-17: 90.3: 26.15
+	Mm
		1223608 DLG1_MOUSE (30-615): 1.69e-69: 244: 13.93		DLG4_MOUSE (1002-1108): 8.45e-17: 88.7: 29.91