HitPredict

Interactor 1: BLK (P51451)
Tyrosine-protein kinase Blk (EC 2.7.10.2) (B lymphocyte kinase) (p55-Blk)
Gene: BLK

Interactor 2: TAGAP (Q8N103)
T-cell activation Rho GTPase-activating protein (T-cell activation GTPase-activating protein)
Gene: TAGAP

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	RhoGAP~SH3_1
Common GO terms	GO:0005829 - cytosol
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 505 Hs			1 731
+	Hs
		440109 LCK_HUMAN (1-505): 0: 568: 59.15		RHG21_HUMAN (4-602): 1.01e-88: 307: 18.52
+	Hs
		463571 LYN_HUMAN (1-505): 0: 551: 59.77		RHG21_HUMAN (4-602): 1.01e-88: 307: 18.52
+	Hs
		156400 FYN_HUMAN (1-503): 0: 561: 54.56		RHG33_HUMAN (44-586): 1.01e-75: 268: 15.61
+	Mm
		813524 FYN_MOUSE (1-503): 0: 560: 54.38		RHG33_MOUSE (44-588): 1.57e-74: 264: 15.27
+	Hs
		67601 LCK_HUMAN (1-505): 0: 568: 59.15		RHG32_HUMAN (52-561): 4.69e-71: 255: 16.52
+	Hs
		440117 LCK_HUMAN (1-505): 0: 568: 59.15		RHG17_HUMAN (68-515): 1.44e-71: 252: 19.67
+	Hs
		67602 FYN_HUMAN (1-503): 0: 561: 54.56		RHG32_HUMAN (52-561): 4.69e-71: 255: 16.52
+	Hs
		67608 SRC_HUMAN (1-503): 0: 559: 54.22		RHG32_HUMAN (52-561): 4.69e-71: 255: 16.52
+	Hs
		557346 SRC_HUMAN (1-503): 0: 559: 54.22		RHG17_HUMAN (68-515): 1.44e-71: 252: 19.67
+	Hs
		67603 LYN_HUMAN (1-505): 0: 551: 59.77		RHG32_HUMAN (52-561): 4.69e-71: 255: 16.52
+	Hs
		473485 HCK_HUMAN (1-505): 0: 574: 62.92		3BP1_HUMAN (64-385): 2.59e-62: 223: 23.17
+	Hs
		463758 LYN_HUMAN (1-505): 0: 551: 59.77		RGAP1_HUMAN (8-363): 1.76e-68: 238: 17.87
+	Hs
		557256 SRC_HUMAN (1-503): 0: 559: 54.22		RHG01_HUMAN (29-282): 2.49e-66: 227: 27.91
+	Hs
		463636 LYN_HUMAN (1-505): 0: 551: 59.77		RHG12_HUMAN (62-278): 2.32e-64: 231: 24.43
+	Hs
		557546 SRC_HUMAN (1-503): 0: 559: 54.22		3BP1_HUMAN (64-385): 2.59e-62: 223: 23.17
+	Hs
		362308 ABL1_HUMAN (54-504): 1.24e-162: 492: 41.09		RHG17_HUMAN (68-515): 1.44e-71: 252: 19.67
+	Hs
		362420 ABL1_HUMAN (54-504): 1.24e-162: 492: 41.09		3BP1_HUMAN (64-385): 2.59e-62: 223: 23.17
+	Hs
		1054119 BTK_HUMAN (4-498): 2.25e-156: 461: 34.31		RHG17_HUMAN (68-515): 1.44e-71: 252: 19.67
+	Mm
		362439 ABL1_MOUSE (54-504): 9.55e-163: 492: 41.30		3BP1_MOUSE (64-412): 1.29e-61: 220: 23.45