HitPredict

Interactor 1: NCS1 (P62166)
Neuronal calcium sensor 1 (NCS-1) (Frequenin homolog) (Frequenin-like protein) (Frequenin-like ubiquitous protein)
Gene: NCS1

Interactor 2: M3K9 (P80192)
Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage kinase 1)
Gene: MAP3K9

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.811

Property	Details
Experiments	33961781, 32707033
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	EF-hand_1~Pkinase, EF-hand_7~Pkinase
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 190 Hs			1 1104
+	Hs
		740653 HPCL1_HUMAN (1-184): 6.31e-54: 171: 60.87		M3K9_HUMAN (1-1104): 0: 794: 100.00
+	Hs
		945769 HPCA_HUMAN (1-184): 6.19e-52: 166: 59.78		M3K9_HUMAN (1-1104): 0: 794: 100.00
+	Hs
		740655 HPCL1_HUMAN (1-184): 6.31e-54: 171: 60.87		M3K10_HUMAN (44-1086): 0: 584: 52.04
+	Hs
		950449 HPCA_HUMAN (1-184): 6.19e-52: 166: 59.78		M3K10_HUMAN (44-1086): 0: 584: 52.04
+	Hs
		740665 HPCL1_HUMAN (1-184): 6.31e-54: 171: 60.87		M3K21_HUMAN (56-1104): 0: 575: 48.30
+	Hs
		901307 NCALD_HUMAN (1-184): 1e-52: 168: 60.33		M3K21_HUMAN (56-1104): 0: 575: 48.30
+	Hs
		950455 HPCA_HUMAN (1-184): 6.19e-52: 166: 59.78		M3K21_HUMAN (56-1104): 0: 575: 48.30
+	Hs
		906765 NCS1_HUMAN (1-190): 3.67e-49: 159: 100.00		M3K21_HUMAN (56-1104): 0: 575: 48.30
+	Hs
		740661 HPCL1_HUMAN (1-184): 6.31e-54: 171: 60.87		M3K11_HUMAN (42-905): 8.76e-144: 454: 44.66
+	Hs
		901304 NCALD_HUMAN (1-184): 1e-52: 168: 60.33		M3K11_HUMAN (42-905): 8.76e-144: 454: 44.66
+	Hs
		950452 HPCA_HUMAN (1-184): 6.19e-52: 166: 59.78		M3K11_HUMAN (42-905): 8.76e-144: 454: 44.66
+	Hs
		906763 NCS1_HUMAN (1-190): 3.67e-49: 159: 100.00		M3K11_HUMAN (42-905): 8.76e-144: 454: 44.66