HitPredict

Interactor 1: PRS8 (P62195)
26S proteasome regulatory subunit 8 (26S proteasome AAA-ATPase subunit RPT6) (Proteasome 26S subunit ATPase 5) (Proteasome subunit p45) (Thyroid hormone receptor-interacting protein 1) (TRIP1) (p45/SUG)
Gene: PSMC5

Interactor 2: TP53B (Q12888)
TP53-binding protein 1 (53BP1) (p53-binding protein 1) (p53BP1)
Gene: TP53BP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	22990118
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0045893 - positive regulation of DNA-templated transcription
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 406 Hs			1 1972
+	Hs
		906818 PRS4_HUMAN (4-396): 7.85e-130: 382: 46.31		TP53B_HUMAN (1-1972): 0: 766: 100.00
+	Hs
		798644 PRS6B_HUMAN (1-399): 6.4e-122: 361: 41.86		TP53B_HUMAN (1-1972): 0: 766: 100.00
+	At
		99347 PRS4A_ARATH (19-396): 1.25e-158: 455: 47.62		F4KHD5_ARATH (6-1615): 1.33e-42: 174: 9.24
+	Hs
		807673 PRS8_HUMAN (1-406): 1.42e-136: 398: 100.00		MAP1B_HUMAN (50-1591): 3.52e-51: 202: 9.41
+	Hs
		807672 PRS4_HUMAN (4-396): 7.85e-130: 382: 46.31		MAP1B_HUMAN (50-1591): 3.52e-51: 202: 9.41
+	Hs
		798609 PRS6B_HUMAN (1-399): 6.4e-122: 361: 41.86		MAP1B_HUMAN (50-1591): 3.52e-51: 202: 9.41
+	Hs
		907188 PRS8_HUMAN (1-406): 1.42e-136: 398: 100.00		SRRM2_HUMAN (18-1418): 1.61e-14: 82.2: 9.78
+	Hs
		906949 PRS4_HUMAN (4-396): 7.85e-130: 382: 46.31		SRRM2_HUMAN (18-1418): 1.61e-14: 82.2: 9.78
+	Hs
		798785 PRS6B_HUMAN (1-399): 6.4e-122: 361: 41.86		SRRM2_HUMAN (18-1418): 1.61e-14: 82.2: 9.78
+	Pf
		1211294 Q8IJW0_PLAF7 (73-391): 1.06e-109: 331: 51.72		Q8I2B4_PLAF7 (355-962): 4.85e-14: 80.5: 13.67