HitPredict

Interactor 1: NEK4 (P51957)
Serine/threonine-protein kinase Nek4 (EC 2.7.11.1) (Never in mitosis A-related kinase 4) (NimA-related protein kinase 4) (Serine/threonine-protein kinase 2) (Serine/threonine-protein kinase NRK2)
Gene: NEK4

Interactor 2: STK24 (Q9Y6E0)
Serine/threonine-protein kinase 24 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 3) (MST-3) (STE20-like kinase MST3) [Cleaved into: Serine/threonine-protein kinase 24 36 kDa subunit (Mammalian STE20-like protein kinase 3 N-terminal) (MST3/N); Serine/threonine-protein kinase 24 12 kDa subunit (Mammalian STE20-like protein kinase 3 C-terminal) (MST3/C)]
Gene: STK24

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 25798074
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~Pkinase
Common GO terms GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006468 - protein phosphorylation
and 1 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 841
Hs

1 443
+ Hs
+ Rn
+ Hs
+ Hs
+ At
+ Hs
+ Hs
+ Hs
+ At
+ Hs
+ Hs
+ Hs
+ Hs
+ At
+ Dm
+ Hs
+ At
+ Dm
+ Mm

Service provided by Combinatics, Japan

Last updated: 11Aug2025