HitPredict

Interactor 1: 1433E (P62258)
14-3-3 protein epsilon (14-3-3E)
Gene: YWHAE

Interactor 2: TRAK1 (Q9UPV9)
Trafficking kinesin-binding protein 1 (106 kDa O-GlcNAc transferase-interacting protein) (Protein Milton)
Gene: TRAK1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	35271311, 36931259
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0006605 - protein targeting GO:0031966 - mitochondrial membrane
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 255 Hs			1 953
+	Rn
		869343 1433E_RAT (1-255): 4.87e-154: 430: 100.00		HAP1_RAT (91-524): 3.53e-28: 123: 23.20
+	Hs
		909658 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		MRCKA_HUMAN (4-678): 5.5e-23: 108: 10.13
+	Hs
		725130 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		MYH10_HUMAN (9-491): 2.9e-17: 89.5: 10.79
+	Hs
		728460 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		MYH11_HUMAN (196-629): 6.39e-17: 88.3: 11.38
+	Mm
		910349 1433E_MOUSE (1-255): 4.87e-154: 430: 100.00		KI21B_MOUSE (34-515): 4.41e-11: 69.5: 8.52