HitPredict

Interactor 1: IMA5 (P52294)
Importin subunit alpha-5 (Karyopherin subunit alpha-1) (Nucleoprotein interactor 1) (NPI-1) (RAG cohort protein 2) (SRP1-beta) [Cleaved into: Importin subunit alpha-5, N-terminally processed]
Gene: KPNA1

Interactor 2: CHD6 (Q8TD26)
Chromodomain-helicase-DNA-binding protein 6 (CHD-6) (EC 3.6.4.-) (ATP-dependent helicase CHD6) (Radiation-induced gene B protein)
Gene: CHD6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	unassigned3799
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 538 Hs			1 2715
+	Hs
		911225 IMA5_HUMAN (1-538): 2.92e-156: 458: 100.00		CHD3_HUMAN (53-1466): 0: 986: 25.74
+	Hs
		138674 IMA4_HUMAN (3-538): 5.05e-151: 444: 45.91		CHD3_HUMAN (53-1466): 0: 986: 25.74
+	Hs
		910870 IMA1_HUMAN (3-538): 4.57e-150: 442: 44.36		CHD3_HUMAN (53-1466): 0: 986: 25.74
+	Hs
		253631 IMA7_HUMAN (1-538): 1.96e-160: 469: 80.48		CHD4_HUMAN (81-1466): 0: 935: 24.81
+	Hs
		911319 IMA5_HUMAN (1-538): 2.92e-156: 458: 100.00		CHD5_HUMAN (44-1466): 0: 939: 23.08
+	Hs
		142552 IMA3_HUMAN (1-538): 2.06e-156: 458: 45.84		CHD4_HUMAN (81-1466): 0: 935: 24.81
+	Hs
		911248 IMA5_HUMAN (1-538): 2.92e-156: 458: 100.00		CHD4_HUMAN (81-1466): 0: 935: 24.81
+	Hs
		179046 IMA6_HUMAN (1-538): 3.86e-153: 450: 79.59		CHD4_HUMAN (81-1466): 0: 935: 24.81
+	Hs
		910901 IMA1_HUMAN (3-538): 4.57e-150: 442: 44.36		CHD4_HUMAN (81-1466): 0: 935: 24.81
+	Hs
		703284 IMA5_HUMAN (1-538): 2.92e-156: 458: 100.00		SMCA1_HUMAN (340-1360): 0: 873: 27.33
+	Hs
		243579 IMA5_HUMAN (1-538): 2.92e-156: 458: 100.00		SMCA5_HUMAN (347-1382): 0: 860: 26.27
+	Hs
		911414 IMA5_HUMAN (1-538): 2.92e-156: 458: 100.00		CHD7_HUMAN (1532-2715): 0: 784: 24.96
+	Zm
		11422 A0A1D6FC42_MAIZE (4-538): 2.62e-154: 453: 51.29		A0A1D6IBX9_MAIZE (128-1181): 0: 737: 28.89
+	Zm
		12626 A0A1D6FMC0_MAIZE (4-538): 8.85e-152: 448: 47.96		A0A1D6IBX9_MAIZE (128-1181): 0: 737: 28.89
+	Hs
		253698 IMA7_HUMAN (1-538): 1.96e-160: 469: 80.48		CHD8_HUMAN (2045-2220): 4.11e-44: 180: 25.79
+	Mm
		1068804 IMA5_MOUSE (1-538): 5.98e-155: 455: 97.77		CHD8_MOUSE (2045-2220): 8.17e-46: 185: 25.26
+	Hs
		142624 IMA3_HUMAN (1-538): 2.06e-156: 458: 45.84		CHD8_HUMAN (2045-2220): 4.11e-44: 180: 25.79
+	Hs
		911389 IMA5_HUMAN (1-538): 2.92e-156: 458: 100.00		CHD8_HUMAN (2045-2220): 4.11e-44: 180: 25.79
+	Mm
		204700 IMA4_MOUSE (3-538): 3.86e-153: 449: 46.10		CHD8_MOUSE (2045-2220): 8.17e-46: 185: 25.26
+	Hs
		179084 IMA6_HUMAN (1-538): 3.86e-153: 450: 79.59		CHD8_HUMAN (2045-2220): 4.11e-44: 180: 25.79