Interactor 1: PRS10 (P53549)
26S proteasome subunit RPT4 (26S protease subunit SUG2) (Proteasomal cap subunit)
Gene: RPT4
Interactor 2: PRS8 (Q01939)
26S proteasome regulatory subunit 8 homolog (Protein CIM3) (Protein SUG1) (Tat-binding protein TBY1)
Gene: RPT6
Species: Saccharomyces cerevisiae S288C
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.94 | 1.00 | 0.970 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 8955118, 16554755, 18467557, 36621624, 23900548, 37968396, 19061648, 31848235 |
| Identification Methods | two hybrid, molecular sieving, coimmunoprecipitation, affinity chromatography technology, protein complementation assay, cross-linking study, dihydrofolate reductase reconstruction, tandem affinity purification |
| Interaction Type | physical association, direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | AAA~AAA, AAA~AAA_lid_3, AAA~Prot_ATP_ID_OB_C, AAA_lid_3~AAA_lid_3, Prot_ATP_ID_OB_C~Prot_ATP_ID_OB_C |
| Common GO terms | GO:0000502 - proteasome complex GO:0005524 - ATP binding GO:0005634 - nucleus GO:0006289 - nucleotide-excision repair GO:0008540 - proteasome regulatory particle, base subcomplex and 8 others more... |
| Homologous interactions | 19 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
